81 citations
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February 2000 in “Anti-cancer drugs” In this pilot study, Doxil at 60 mg/m² every 4 weeks showed activity against hormone-refractory prostate cancer but was limited by severe mucocutaneous toxicities.
56 citations
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November 1993 in “Journal of The American Academy of Dermatology” Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.
29 citations
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September 2020 in “International Journal of Molecular Sciences” This review outlines the current state of freeze-dried platelet-rich plasma (FD-PRP) research, emphasizing its use in wound healing, lumbar fusion, knee conditions, and dentistry, but reports no new clinical findings.
2 citations
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January 2025 in “Frontiers in Pharmacology” In a rat model of benign prostatic hyperplasia, this study found that purple corn extract may improve symptoms by inhibiting prostate enlargement, reducing androgen receptor signaling, and exerting anti-inflammatory effects.
June 2025 in “Dermatologic Surgery” This article reviews multiple noncutaneous manifestations of pityriasis rubra pilaris, such as subungual hyperkeratosis and hair loss, but reports no new clinical results.
210 citations
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February 2008 in “Nature genetics” This study found mutations in the P2RY5 gene that are linked to autosomal recessive woolly hair in Pakistani families, implicating it in hair texture determination.
109 citations
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February 2018 in “CB/Current biology” This study concluded that the receptor-like kinase ERULUS, regulated by auxin, is crucial for modulating cell wall composition and pectin dynamics during root hair growth in Arabidopsis.
August 2024 in “Quality in Sport” This review highlights the positive effects of platelet-rich plasma in aesthetic and regenerative medicine, particularly for skin rejuvenation, anti-aging, hair reconstruction, and wound healing, but it reports no new clinical results.
4 citations
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January 1994 in “Current Opinion in Endocrinology & Diabetes” This review discusses multiple physiological roles of parathyroid hormone-related protein, such as cartilage mineralization and hair follicle regulation, and reports no new experimental results.
January 2017 in “Hair transplant forum international” This study examined the effects of platelet-rich plasma (PRP) treatment on women with female androgenetic alopecia in a double-blind, placebo-controlled pilot trial, but specific results were not reported in the abstract.
9 citations
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May 2024 in “Cureus” This review discusses the role of platelet-rich plasma in assisted reproductive technology for enhancing endometrial receptivity and reports promising outcomes.
17 citations
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October 2023 in “Molecules” In laboratory and artificial skin model experiments, this study found that plant-derived PDRN from Korean ginseng effectively promoted skin cell regeneration and strengthened the skin barrier, suggesting a sustainable alternative to animal-derived PDRN.
3 citations
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June 2022 in “European journal of human genetics” This study reports the first cases of recessive KRT17-related pachyonychia congenita involving all ectodermal derivatives in seven members of two consanguineous Pakistani families.
6 citations
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November 2017 in “Scientific reports” This study found that a novel R343H mutation in the vitamin D receptor gene impairs its transcription activity, contributing to hereditary vitamin D-resistant rickets and alopecia in the affected family.
April 2017 in “Journal of Investigative Dermatology” This study found that the PON1 192 R allele was associated with an increased risk of psoriasis and altered lipid profiles in patients from Western Mexico.
45 citations
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July 2025 in “Journal of Medicinal Chemistry” This article discusses the development and clinical progress of PROTAC technology, particularly focusing on the New Drug Application for vepdegestrant, an estrogen receptor-targeting PROTAC, marking significant advancements in targeted protein degradation therapies.
1 citations
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March 2023 in “Frontiers in Cardiovascular Medicine” A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.
May 2022 in “The Egyptian Journal of Hospital Medicine” This review discusses the role of platelet-rich plasma in dermatological treatments and reports no new clinical results, indicating its increasing use among dermatologists.
January 2026 in “American Journal of Medical Genetics Part A” The researchers reported two brothers with a new variant of X-linked trichothiodystrophy associated with an RNF113A gene mutation, highlighting features such as intellectual disability and growth failure, but without previously reported endocrinological or genital abnormalities, underlining the importance of genetic counseling for such variants.
December 2025 in “Journal of Human Immunity” In this case report, a 37-year-old patient with APECED showed significant clinical improvement, including hair regrowth and resolution of skin issues, after 11 months of treatment with ruxolitinib, highlighting the potential of JAK inhibitors in managing this complex autoimmune disease.
November 2023 in “The Journal of Urology” The conclusion is that future trials should report specific details about the PRP composition to better understand its effects on urologic conditions.
October 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study evaluated the effects of platelet-rich plasma (PRP) on endometriosis but found no statistically significant overall difference in endometriotic foci size reduction between treated and control groups.
14 citations
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August 2015 in “Endocrinology” This study describes the development of a monoclonal antibody, 005-C04, which blocks PRLR-mediated signaling, suggesting its potential for furthering understanding of PRLR's role in health and disease.
94 citations
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April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study describes the first case of female pseudohermaphroditism due to a novel homozygous glucocorticoid receptor gene mutation, indicating possible pre- and postnatal virilization in affected females.
September 2020 in “Research Square (Research Square)” This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by modulating key signaling pathways, suggesting a novel therapeutic approach for degenerative diseases.
1 citations
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December 2019 in “Protetyka Stomatologiczna” This review discusses the use of platelet-rich fibrin in medical fields, especially dentistry, and reports no new clinical results.
July 1989 in “British Journal of Dermatology” Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.
1 citations
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February 2020 in “International journal of research in dermatology” This review discusses the potential applications of platelet rich plasma in dermatology and cosmetology for conditions like alopecia and skin rejuvenation and reports no new clinical findings.
In this study, Norwegian researchers followed over 350 patients with porphyria cutanea tarda for an average of 7 years and found that 25% experienced biochemical relapse, suggesting the importance of routine follow-up for early detection and management.
5 citations
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March 2023 in “Journal of the American Academy of Dermatology” This study reports that prurigo pigmentosa did not appear linked to a specific common trigger such as the ketogenic diet, but suggests that oral antibiotics might effectively resolve the condition.