108 citations
,
August 2017 in “Clinical, Cosmetic and Investigational Dermatology” This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.
68 citations
,
December 2014 in “Cell Biochemistry and Function” This review examines the role of nuclear hormone receptors in skin wound repair processes and reports no new clinical results, highlighting the importance of their interaction with skin cells for effective healing.
66 citations
,
August 2011 in “Parasitology Research” This study found that Mentha pulegium essential oil had a stronger protoscolicidal effect against Echinococcus granulosus in vitro than Mentha piperita, showing dose- and time-dependent effects.
65 citations
,
February 2015 in “Neuro-Oncology” In this study, four children with recurrent atypical teratoid rhabdoid tumors experienced disease stabilization or regression after treatment with alisertib, suggesting its potential role in future trials for this condition.
58 citations
,
December 2017 in “Journal of The European Academy of Dermatology and Venereology” This review highlights that microneedling shows some promise for improving hair growth in alopecia, particularly when used with other treatments, though more research is needed to establish its efficacy and protocols.
57 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
53 citations
,
May 1995 in “Journal of The American Academy of Dermatology” This article describes two cases where essential alopecia was the initial sign of syphilitic infection, examining the clinical and histopathologic features observed.
44 citations
,
February 2021 in “Scientific Reports” This study found that specific mutations in the spike protein of SARS-CoV-2 may significantly alter its structure and affect how it binds to certain inhibitors, but experimental studies are needed to confirm potential clinical implications.
39 citations
,
November 1984 in “Journal of Cardiovascular Pharmacology” Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.
29 citations
,
January 2009 in “International Journal of Trichology” This report describes two cases of gynecomastia linked to the use of Finasteride (Propecia®) for treating androgenetic alopecia, highlighting a rare but important side effect.
28 citations
,
July 2002 in “Australasian Journal of Dermatology” This case report describes a 27-year-old woman with lupus erythematosus whose biopsy findings indicated that lupus panniculitis can mimic alopecia areata, leading to temporary hair loss.
28 citations
,
May 1994 in “The Journal of Urology” This study found that topical application of 2% minoxidil solution was not effective in improving erectile dysfunction in the majority of participants.
26 citations
,
June 2020 in “Polymers” This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.
24 citations
,
June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” This review discusses the potential of microneedle arrays for drug delivery and in the cosmetic market, but reports no new clinical results; factors for commercial therapeutic use are explored.
23 citations
,
September 2018 in “Dermatologic Therapy” This article explains that skin microneedling promotes skin regeneration by creating microinjuries, which stimulate collagen and elastin production, making it effective for treating various skin issues with high effectiveness, limited side effects, and a short recovery time.
22 citations
,
November 1998 in “Archives of Dermatology” This article presents 12 theses distinguishing alternative and regular medicine in Germany, reporting no new clinical results; the authors argue that the current integration of alternative methods in universities is misguided.
21 citations
,
December 2012 in “European journal of pharmaceutics and biopharmaceutics” This study suggests that using particle-bound antiseptics may provide more effective and longer-lasting skin antisepsis compared to their non-particulate forms.
19 citations
,
October 2020 in “Biomedical Microdevices” This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.
17 citations
,
January 1996 in “Aesthetic Plastic Surgery” This study suggests that the tumescent technique effectively provides anesthesia and reduces bleeding during hair micrografting, eliminating the need for multiple needle injections or nerve blocks.
16 citations
,
July 2002 in “Australasian Journal of Dermatology” This case report illustrates the risk of skin necrosis in patients with high antiphospholipid antibody levels after stopping anticoagulation therapy, highlighting the necessity for careful monitoring.
16 citations
,
July 2000 in “Dermatologic surgery” This paper contains author contact information and disclosures without reporting new research findings or results.
15 citations
,
May 2005 in “Seminars in Plastic Surgery” This article details techniques for eyebrow and eyelash reconstruction surgery with hair follicular unit transplantation but reports no new clinical results; the author describes the advantages over other methods.
15 citations
,
July 2002 in “Australasian Journal of Dermatology” In this case report, two plywood mill workers developed allergic contact dermatitis due to exposure to uncured phenol-formaldehyde resin, not sawdust as initially suspected.
15 citations
,
September 1984 in “Veterinary Clinics of North America: Small Animal Practice” The document explains various skin conditions in cats and how to diagnose and treat them.
15 citations
,
March 1981 in “Journal of The American Academy of Dermatology” This study found that fiber implantation for pattern baldness frequently led to complications, including infection and scarring, and poses carcinogenesis risks, leading authorities to discourage its use.
13 citations
,
September 2020 in “Dermatologic Therapy” This review discusses the use of microneedling for androgenetic alopecia and finds it promising for enhancing hair density and thickness, especially when combined with other treatments, but notes no standardized protocol exists yet.
13 citations
,
February 2006 in “Clinical and Experimental Dermatology” A benign tumor developed at a girl's BCG vaccination site, not previously linked to the vaccine.
12 citations
,
July 2015 in “Veterinary Dermatology” This study observed that microneedling induced significant hair regrowth and reduced hyperpigmentation in two Pomeranians with alopecia X, with stable results over 12 months.
11 citations
,
January 1961 in “Archives of dermatology” In this study, corticosteroid injections were found to be more effective than saline for inducing hair regrowth in cases of alopecia areata with long-duration and extensive hair loss.
10 citations
,
January 2016 in “Elsevier eBooks” This chapter reviews the role of nanoparticles in wound healing, exploring current therapies, developments, and future directions, but reports no new clinical results.