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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Photodynamic Therapy is an effective treatment for mild to severe acne.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.