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Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

People with the same genetic mutation for Woodhouse-Sakati syndrome can have different symptoms.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

Men with vertex baldness may have a higher risk of developing prostate cancer, but more research is needed to confirm this.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Some antiseizure medications can cause cosmetic problems like hair loss, excessive hair growth, acne, and gum overgrowth.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Skin problems like acne and excess hair in PCOS are common and linked to being overweight.

Women with PCOS may have higher bad cholesterol and are at risk for blood sugar issues; lifestyle changes are recommended.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

Personalized diets, like the Mediterranean Diet and low carb diets, can help manage PCOS symptoms in obese women, and probiotics may enhance weight loss and improve metabolic health. More research is needed to find the best diet strategies.

Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.

Androgenetic alopecia in teens is linked to obesity and other metabolic risks, needing early diagnosis and management.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Girls had higher stress hormone levels during school due to social and emotional issues, while boys had higher overall hormone levels with slight changes when school started.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

A 20-year-old woman with a rare form of Turner syndrome showed improvement with hormonal therapy and needs comprehensive care.

The new rodent model successfully mimics non-lean human PCOS symptoms.

Sex hormones likely don't affect atopic dermatitis in adolescents and adults.

Vulvar acne, also known as "vulvar Fordyce adenitis", is a condition causing painful bumps on the labia, and it's not always effectively treated with common acne medications, but isotretinoin has shown promise.

A patient with a scalp condition and benign skin tumor experienced hair loss and did not improve with treatment, choosing not to have surgery despite a small cancer risk.