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PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Vitamin D3 and parathyroid hormone-related peptide may have important uses in skin treatments.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

No treatment fully prevents hair loss from chemotherapy yet.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Certain medications, including some immune drugs, contraceptives, and hair loss treatments, are often linked to hair loss.

New treatments for hair loss are being developed using molecular biology.

No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.

A protein combining parathyroid hormone and collagen helped hair regrow in mice with a hair loss condition.

PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

The control system for hair growth cycles is not well understood and needs more research.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

PTH-CBD could help prevent and treat hair loss caused by chemotherapy in mice.

A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Growth factors are crucial for hair development and could help treat hair diseases.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.

RANK-RANKL signaling is essential for hair growth and skin health.