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Ustekinumab might work for severe psoriasis, but more research is needed to be sure.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.

Clofazimine effectively treated a rare skin condition with ash-gray patches.

The document is a detailed medical reference on skin and genetic disorders.

Clofazimine may be effective for treating ashy dermatosis.

Clofazimine successfully treated a man's ashy dermatosis, clearing his skin lesions.

Clofazimine effectively treated ashy dermatosis in a patient.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Zinc is effective for treating various skin conditions, including warts and acne.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Animal models have helped understand hair loss from alopecia areata and find new treatments.