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30-60 / 1000+ resultsresearch Delayed Puberty
This article reviews various causes and diagnostic approaches to delayed puberty in boys and girls and does not report any new clinical findings; it emphasizes the importance of distinguishing between different underlying conditions.
research Virilizing Adrenocortical Oncocytoma in a Child: A Case Report
This case report describes a rare instance of functioning adrenocortical oncocytoma in a 14-year-old girl with virilization and reviews related literature.
research Hyperandrogenism in Adolescent Girls
This article reviews the challenges in diagnosing mild hyperandrogenism in adolescent girls, discussing potential causes like PCOS and treatment options, but reports no new clinical results.
research Hyperandrogenism in Adolescent Girls
This article reviews the differential diagnosis of mild hyperandrogenism in adolescent girls, discussing potential causes such as PCOS and nonclassic adrenal hyperplasia, but presents no new data.
research Syndromes of Severe Insulin Resistance (SSIRs)
This review discusses various syndromes of severe insulin resistance, their biochemical and clinical features, and potential therapeutic options, but it reports no new clinical results.
research SUN-LB2 Undescended Testicle and Short Stature as Manifestation of Pituitary Stalk Interruption Syndrome a Report From Saudi Arabia
This case report highlights the importance of considering pituitary stalk interruption syndrome as a potential diagnosis for patients with short stature, as early detection may allow those affected to achieve normal height.
research Normal Pubertal Development: Part II: Clinical Aspects of Puberty
This article reviews various aspects of puberty, particularly focusing on the staging of sexual maturity and the factors influencing pubertal onset, but reports no new empirical results.
research Pubertal Development
This article reviews puberty's onset, development, and the factors affecting it, including nutrition, obesity, and gender dysphoria, and reports no new clinical results.
research Case Report: Disorder of Sex Development 46, XY with Proximal Hypospadias in a 10-Year-Old Twin Boy: Disorder of Sex Development 46, XY with Proximal Hypospadias
This case report describes a 10-year-old twin boy with proximal hypospadias and undescended testis, highlighting the diagnostic and treatment evaluations for associated sex development disorders.
research Growing Up Fast: Managing Autism Spectrum Disorder and Precocious Puberty
This case report describes a 4-year-old boy with autism and a rare condition causing precocious puberty, where treatment for hyperandrogenism unexpectedly intensified his aggressive behavior.
research Central Precocious Puberty and Sjogren-Larsson Syndrome in a Child: A Rare Case Report
In this case report, a 9-year-old boy with Sjogren-Larsson syndrome was also diagnosed with central precocious puberty, showing genetic mutations and increased hormone levels; he was treated with triptorelin acetate for CPP but experienced growth delay during follow-up.
research A Teenage Girl with Unexpected Pubertal Changes
This case report described a 9-year-old girl initially suspected to have complete androgen insensitivity syndrome, whose laboratory tests later suggested an alternative diagnosis involving atypical steroid metabolism patterns and hormonal responses.
research Disorders linked to insufficient androgen action in male children
This review discusses the role of genetic mutations and environmental endocrine disruptors in insufficient androgen action, which can result in conditions like hypospadias, cryptorchidism, and micropenis, during male fetal development.
research The pubertal presentation of polycystic ovary syndrome (PCOS)
This study found that adolescent girls with PCOS experienced earlier thelarche and menarche compared to controls, and the authors suggest these patterns may relate to hyperandrogenism and increased body mass index.
research Case 5: A Very Tall 7-year-old Boy with Medulloblastoma
This case report describes a 7-year-old boy with medulloblastoma who developed central precocious puberty, potentially triggered by the mass effect of the tumor, which was managed with leuprolide.
research Normal Pubertal Development: Part I: The Endocrine Basis of Puberty
This article reviews the physiological changes underlying normal pubertal milestones and emphasizes the importance of understanding these changes to assess pubertal abnormalities, without reporting new clinical findings.
research Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat
This study found that nuclear androgen receptor expression was enhanced by dihydrotestosterone in rat gubernacular mesenchyme, but this did not affect muscle morphology or matrix composition during fetal development.
research A rabbit model of hypospadias induced by finasteride
This study established a stable rabbit model of hypospadias using finasteride, finding varied rates of the condition's severity and associated testicular retention across different gestation day treatments.
research Androgen Biosynthesis and Gene Defects
This article reviews the clinical and biochemical features of genetic mutations affecting dihydrotestosterone production and their potential role in male pseudo-hermaphroditism, but presents no new clinical results.
research Systematic analyses of murine masculinization processes based on genital sex differentiation parameters
This study introduces genital sex differentiation parameters (GSDP) to analyze sexual differences in external genitalia and perineum development in mice, revealing varied sensitivity to androgen inhibition in genital structures.
research Disorders linked to insufficient androgen action in male children
This article reviews the potential causes of insufficient androgen action during fetal development, such as enzyme and receptor gene mutations or environmental disruptors, but reports no new results.
research Polypoid Cystitis and Bilateral Hydronephrosis Mimicking Urothelial Carcinoma
This report discusses a rare case of polypoid cystitis in a 45-year-old Asian man, which mimicked a bladder tumor and caused bilateral upper tract obstruction that was successfully treated through staged endoscopic management, ureteral stenting, and oral steroids.
research Case 1: Severe acne – not just skin deep
This case report describes a 10-year-old girl with advanced puberty signs and resistant acne, highlighting potential early-onset puberty with associated growth patterns.
research Prevention and treatment of experimental prostate cancer in lobund-wistar rats. I. Effects of estradiol, dihydrotestosterone, and castration
This study found that early treatment with estradiol or dihydrotestosterone significantly reduced prostate adenocarcinoma development in Lobund-Wistar rats, while later treatments were ineffective.
research Pesticides Exposure and Risk of Hypospadias
This article reviews the development, classification, and embryology of hypospadias and reports no new findings; the authors highlight its unknown cause and discuss associated anatomical anomalies.
research Transient scrotal hair growth in infancy
This case report details an instance of transient scrotal hair development in a UK infant, which spontaneously resolved by 7 months of age, with no underlying pathology identified.
research PMON319 A Pure Androgen Secreting Adrenal - Cortical Tumor in a 13 Year Old Female
This case study reports a rare instance of a virilizing androgen-only secreting adrenal cortical adenoma in a 13-year-old, with symptom resolution after surgical removal.
research An unusual case of quadruple polyorchidism in a human cadaver mimicking bilateral lipoma
This study reports a rare case of polyorchidism in a 96-year-old male cadaver, suggesting a new classification based on anatomical and histological findings to aid in accurate diagnosis.
research Precocious puberty in a 24 month old Nigerian girl: case report
This case report describes a 24-month-old girl from Nigeria with idiopathic precocious puberty, emphasizing the financial barriers to necessary treatment in developing countries.