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Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Male pattern baldness involves hormones and cell signals affecting hair growth.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Applying a special compound can promote hair growth without harmful side effects.

KGF and activin are crucial for skin healing and repair.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.