211 citations
,
January 2019 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
92 citations
,
September 2019 in “ACS nano” A wearable device using electric stimulation can significantly improve hair growth.
2 citations
,
January 2019 in “Elsevier eBooks” Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
82 citations
,
March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
39 citations
,
February 2012 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
16 citations
,
February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” MED1 is essential for normal hair growth and maintaining hair follicle stem cells.
53 citations
,
October 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Topical calcitriol-analogs can reduce hair loss caused by chemotherapy.
321 citations
,
January 2010 in “Journal of Dermatological Science” Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
5 citations
,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
12 citations
,
April 2019 in “Scientific Reports” A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.
July 2023 in “Cosmetics” New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
58 citations
,
August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.
73 citations
,
November 2000 in “Proceedings of the National Academy of Sciences of the United States of America” There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.
1 citations
,
June 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
61 citations
,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
2 citations
,
August 2020 in “Clinical, Cosmetic and Investigational Dermatology” The hair-growth formula with L-cystine helps protect and grow hair cells.
1010 citations
,
August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
5 citations
,
October 2012 in “Journal of Investigative Dermatology” Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
20 citations
,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
14 citations
,
January 2021 in “Stem cell research & therapy” Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
29 citations
,
August 2015 in “Journal of Investigative Dermatology” Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.
25 citations
,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
39 citations
,
June 2013 in “Journal of Cosmetic Dermatology” Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.
19 citations
,
April 2016 in “Journal of Ginseng Research” Korean Red Ginseng may protect against hair loss caused by chemotherapy.
2 citations
,
December 2007 in “Journal of Investigative Dermatology” Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.
4 citations
,
July 2018 in “Electronic Journal of Biotechnology” All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.
14 citations
,
March 2019 in “Journal of Cosmetic Dermatology” Activated platelet-rich plasma helps hair growth by boosting growth factors and cell growth pathways in hair cells.
13 citations
,
April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
10 citations
,
January 2009 in “Elsevier eBooks” Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.