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Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

The document concludes that hair loss is common and can be treated with medications like minoxidil or surgical options, and it significantly affects people's psychological well-being.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Some medications can cause hair loss, and it's important to track when the hair loss starts after taking a new medication.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

Sex hormones, especially androgens, play a key role in causing acne.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.

Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.

Nanotechnology improves Clomiphene citrate's effectiveness and reduces side effects for treating ovulatory disorders.

The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

New compounds may soon be tested to treat excessive hair growth in women.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.