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Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Skin aging reflects overall body aging and can indicate internal health conditions.

Arrector pili muscle regulates hair follicle stem cells, DNA methylation needed for hair cycling, and Wnt/B-catenin signaling starts hair growth.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.

Lower SMAD2/3 activation predicts more severe skin cancer.

Deleting Snai2 and Snai3 causes fatal autoimmunity.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.