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150-180 / 1000+ resultsresearch Reversible severe myopathy during treatment with finasteride
research Cushings syndrome complicating pemphigoid gestationis
This case study reports a pregnant woman with bullous pemphigoid who developed Cushing syndrome following steroid treatment, emphasizing the need for careful management of steroid-related complications.
research A Randomised Controlled Trial Comparing the Therapeutic Efficacy and Safety of Oral Cyclosporine and Oral Betamethasone Minipulse Therapy in the Treatment of Alopecia Areata
This study found that oral cyclosporine therapy was more effective than betamethasone mini-pulse therapy for treating alopecia areata, with a better patient-reported outcome on hair regrowth, despite a higher incidence of mild, reversible adverse effects in the cyclosporine group.
research Weekly azathioprine pulse versus betamethasone oral mini-pulse in the treatment of moderate-to-severe alopecia areata
This study found that azathioprine pulse therapy and betamethasone both effectively managed alopecia areata with similar hair regrowth results, though betamethasone had significantly more side effects, suggesting azathioprine as a preferable alternative to corticosteroids.
research ALOPECIA UNIVERSALIS TREATED WITH ORAL CYCLOSPORINE A AND PREDNISOLONE: IMMUNOLOGIC STUDIES
In this study, treating refractory alopecia universalis with low-dose cyclosporine A and prednisolone improved symptoms, with no recurring alopecia six months post-treatment and enhancements in immunologic function.
research 17‐beta estradiol and prednisolone as potential stimulators of hair re‐growth in chemotherapy‐induced human hair follicle damage via ‘dystrophic catagen’ promotion?
This study suggests that combining 17-beta estradiol with prednisolone could accelerate hair regrowth after chemotherapy-induced alopecia in humans, based on preclinical findings using an in vitro model.
research Androstanediolglucuronide: A parameter for peripheral androgen activity before and during therapy with cyproterone acetate
This study found that cyproterone acetate significantly reduced both serum 3α-AdiolG levels and hirsutism scores in women with idiopathic hirsutism, PCOS, or 21-hydroxylase deficiency, suggesting its effectiveness in treating excessive hair growth.
research Cyproterone acetate as initial treatment and maintenance therapy for hirsutism
This study found that high-dose cyproterone acetate was effective for treating hirsutism, but 33% of patients felt their condition worsened on low-dose maintenance therapy, despite no significant change in objective measures of hair growth.
research Budesonide for maintenance of remission in Crohn's disease
This study suggests that oral budesonide may not effectively maintain remission in Crohn's disease beyond three months, with minor benefits that are outweighed by increased rates of treatment-related adverse events.
research A comparison of the relative efficacy of antiandrogens for the treatment of acne in hyperandrogenic women
In this study, low doses of cyproterone acetate with ethinylestradiol were as effective as low-dose flutamide in reducing acne severity in hyperandrogenic women, while finasteride was less effective.
research Consecutive Cyproterone Acetate and Estradiol Treatment in Late-Pubertal Transgender Female Adolescents
In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.
research P-017 CUSHING'S SYNDROME DUE TO PRIMARY BILATERAL MACRONODULAR ADRENAL HYPERPLASIA AND METACRONOUS PHEOCHROMOCYTOMA
This case report presents a rare instance of recurrent ACTH-independent Cushing’s syndrome due to PBMAH, coinciding with the development of a pheochromocytoma, highlighting the need for thorough reevaluation in similar recurring cases.
research Desideratum dermatologicum--cause and control of premenstrual acne flare
Taking a small dose of prednisone before menstruation can almost completely prevent premenstrual acne with few side effects.
research Low Cortisol in a Cushingoid Patient
This case report uncovered that hidden dexamethasone in a dietary supplement caused misleading Cushingoid symptoms and lab results, underscoring the risk of undisclosed ingredients in supplements.
research The curative effect of metformin in combination with dyne-35 on the treatment of polycystic ovary syndrome and on the ovulation rate and pregnancy rate
This study found that combining metformin with dyne-35 improved irregular menstruation, acne, and increased ovulation and pregnancy rates more effectively than G'Finn treatment alone in patients with polycystic ovary syndrome.
research Medroxyprogesterone acetate therapy in hirsutism
This study found that subcutaneous injection of medroxyprogesterone acetate was more effective than intramuscular or topical treatments in reducing hair diameter for hirsute females.
research Cyclophosphamide-associated acneiform drug eruption in a patient with multiple myeloma
This report describes a rare case of cyclophosphamide-associated neutrophilic folliculitis, suggesting its inclusion in differential diagnoses for acneiform eruptions.
research Direct access to novel chromeno-pyrimidine-N-oxides via tandem base catalyzed double nucleophilic addition/dehydration reaction
This study reports a new one-pot method for synthesizing chromeno-pyrimidine-N-oxides with high yield from 4-chloro-3-formylcoumarin and aromatic carboximide oximes, confirmed by X-ray analysis.
research Hyperadrenocorticism (Hyperadrenocorticoidism, Hyperadrenocorticalism, Cushing’s Disease, Cushing’s Syndrome)
This review discusses the physicochemical properties, binding mechanisms, and factors affecting corticosteroid-binding globulin (CBG) functions, but reports no new clinical results.
research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications
This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.
research Cyclophosphamide treatment with a comparison in both pediatric rheumatology and pediatric nephrology practices
This study found that clinicians frequently prefer cyclophosphamide over rituximab for induction therapy of childhood-onset systemic lupus erythematosus and ANCA-associated vasculitis, following a high-dose regimen recommended by the NIH.
research PSS20 MEDIATION MODELING AND MEASUREMENT CHARACTERISTICS OF THE ITCH SEVERITY SCORE FROM A PHASE 2B TRIAL OF ORAL CP-690-550 IN PATIENTS WITH MODERATE TO-SEVERE PLAQUE PSORIASIS
This study found that the oral Janus kinase inhibitor CP-690,550 has a direct effect on reducing pruritus in patients with psoriasis, independent of clinician-assessed improvements in psoriasis severity.
research The comparison of treatment with clobetasol propionate 0.05% and topical pimecrolimus 1% treatment in the treatment of alopecia areata
This study found that topical pimecrolimus is as effective as clobetasol propionate for treating alopecia areata, with better tolerability in terms of side effects.
research The use of cyproterone acetate/ethinyl estradiol in hyperandrogenic skin symptoms – a review
This review highlights that Cyproterone acetate combined with ethinylestradiol is highly effective for treating severe acne and hirsutism in women with hyperandrogenism, and it also provides benefits for cycle control and mood improvement, according to the analysis of 78 studies.
research The Efficacy and Safety of a Combination Cytopurine/Pentadecanoic Glyceride Topical Solution on Androgenetic Alopecia: A Randomized Double-Blind Placebo-Controlled Clinical Trial
This study found that the new cytopurine/pentadecanoic glyceride topical solution significantly improved total hair count and reduced daily hair shedding in patients with androgenetic alopecia over 16 weeks, although other measures did not differ from placebo.
research A Comparative Study of Oral Cyclosporine and Betamethasone Minipulse Therapy in the Treatment of Alopecia Areata
This study found that oral cyclosporine was more effective and had fewer side effects than betamethasone minipulse therapy for treating alopecia areata.
research Evaluation Of The Use Of Cyclophosphamide In Children Diagnosed With Steroid Resistant Nephrotic Syndrome Treated In The 3rd Floor Treatment At Fatmawati Hospital
In this study of children with nephrotic syndrome treated with cyclophosphamide, 59.4% achieved remission, and 40.6% experienced side effects including nausea, vomiting, and hair loss.
research ODP342 Panhypopituitarism Induced by CTLA-4 and PD-1/PD-L1 Inhibitor Immunotherapy
This case study reports that immunotherapy with ipilimumab and nivolumab induced hypophysitis in a patient with renal cell carcinoma, emphasizing the need for careful monitoring of endocrine function in such treatments.
research Steroid-sparing effect of mycophenolate mofetil in the treatment of a subepidermal blistering autoimmune disease in a dog : clinical communication
This case report describes how a treatment with mycophenolate mofetil and prednisone may be effective in managing autoimmune subepidermal blistering dermatosis in dogs while allowing for steroid reduction.