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Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.

New treatments for relapsing multiple sclerosis are more effective and convenient but have higher risks of serious side effects.

Thallium is highly toxic, causing severe health issues, and Prussian blue is the best antidote.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Platelet-rich plasma shows promise for treating various female reproductive health issues but requires more research.

Pregnancy can cause normal skin changes, including darkening of certain areas, nail changes, vascular changes, and breast changes like stretch marks.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Babies were mostly born healthy from fathers who took finasteride, but some pregnancies ended early; more research is needed.

Pregnant women with isolated hypothyroxinemia face more health issues, so iodine and folic acid supplements are important before and during early pregnancy.

Hormones and stretching both needed for nipple area skin growth in mice.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Lupus patients' body image issues significantly affect their mental health and need more support.

Hair gets thinner and grayer with age, and density decreases more in men on top and in women on top and back.

Patients with both connective tissue disease and acid reflux are more likely to have certain symptoms and physical signs.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Aging-related hormone changes affect voice quality, especially during puberty, menstruation, pregnancy, and menopause.

Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.

Fear of hair-related issues causes significant mental distress, especially in high-stress women.

Caffeine intake during pregnancy and lactation can cause skin lesions in mother rats and their babies, not linked to cortisol levels.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.

A comprehensive approach to educating patients and managing side effects is crucial for improving adherence to multiple sclerosis treatments and patient quality of life.

Chromium picolinate was better tolerated than metformin for PCOS with fewer side effects.

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

A woman's significant hair loss was linked to rapid weight loss and hormone injections.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.