research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results
Both mouse and rat models are effective for testing alopecia areata treatments.
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research Drug Repositioning: Current Approaches and Their Implications in the Precision Medicine Era
Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Techniques for the Discovery and Evaluation of Drugs Against Alopecia
We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
research Lack of Response to Laser Comb in Spontaneous and Graft-Induced Alopecia Areata in C3H/HeJ Mice
The laser comb did not improve hair regrowth in mice with alopecia areata.
research Alopecia Areata: Animal Models Illuminate Autoimmune Pathogenesis and Novel Immunotherapeutic Strategies
Animal models have helped understand hair loss from alopecia areata and find new treatments.
research Tissue Engineering of Human Hair Follicles Using a Biomimetic Developmental Approach
Researchers created human hair follicles using a new method that could help treat hair loss.
research Alopecia Areata: An Autoimmune Disease Causing Hair Loss
Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
research Alopecia Areata Update
Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
research Effects of the Lexington LaserComb on Hair Regrowth in the C3H/HeJ Mouse Model of Alopecia Areata
The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.
research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata
Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research Recombinant Human Hepatitis B Vaccine Initiating Alopecia Areata: Testing the Hypothesis Using the C3H/HeJ Mouse Model
The hepatitis B vaccine did not cause hair loss in the tested mice.
research T-Cell Reconstitution After Thymus Xenotransplantation Induces Hair Depigmentation and Loss
T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
research Evaluation of Animal Models Suitable for Hair Research and Regeneration
Animal models, especially mice, are essential for advancing hair loss research and treatment.
research The Role of the Skin Microbiome in the Development of Alopecia Areata
The skin's bacteria might influence the development of a hair loss condition called alopecia areata.
research Vaccines, Infections, and Alopecia Areata
Some vaccines, like the hepatitis B vaccine, might be linked to the hair loss condition Alopecia Areata, but more research is needed.
research Alopecia Areata Susceptibility Variant in MHC Region Impacts Expressions of Genes Contributing to Hair Keratinization and Is Involved in Hair Loss
A gene variant increases the risk of a type of hair loss by affecting hair protein production.
research Phytotherapeutic Interventions Using Rodent Models of Hair Loss: Current Research and Future Strategy
Natural products show promise for new hair loss treatments.
research Neuroendocrine Perspectives in Alopecia Areata: Does Stress Play a Role?
Stress might contribute to hair loss in alopecia areata.
research Pathomechanisms of Immune-Mediated Alopecia
The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
research Heat Treatment Increases the Incidence of Alopecia Areata in the C3H/HeJ Mouse Model
Heat treatment increases hair loss in certain mice.
research In Vivo Phytotherapy in BALB/c Athymic Nude Mice: Hair Growth Promotion Using Ficus Religiosa L. and Morus Alba L.
Ficus religiosa and Morus alba extracts improved hair growth and follicle regeneration in mice.
research Modeling of Solar UV-Induced Photodamage on the Hair Follicles in Human Skin Organoids
Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Repurposed Drugs: Current Trends In Drug Discovery
Drug repurposing speeds up development, cuts costs, and uses known safe drugs, but faces challenges like regulations and patents.
research A Human Folliculoid Microsphere Assay for Exploring Epithelial-Mesenchymal Interactions in the Human Hair Follicle
HFMs can help study hair growth and test potential hair growth drugs.
research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.