688 citations
,
June 2007 in “Cell Stem Cell” This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.
249 citations
,
April 2002 in “The FASEB journal” This study provides evidence that human skin contains genes and enzymes necessary for producing serotonin and melatonin.
87 citations
,
December 2016 in “British journal of dermatology/British journal of dermatology, Supplement” This study describes and characterizes four cases of alopecia areata induced by immune checkpoint inhibitor therapy in cancer patients, highlighting the importance of recognizing and managing these hair-related adverse events.
65 citations
,
July 2013 in “International Clinical Psychopharmacology” This review provides an overview of the prevalence and management of side effects of mood-stabilizing drugs in bipolar disorder patients and reports no new clinical results.
57 citations
,
September 2005 in “International Journal of Dermatology” This study reported that chemical relaxants and hair styling practices were associated with scarring hair loss, particularly among women with central centrifugal cicatricial alopecias.
54 citations
,
October 2019 in “Australian Journal of General Practice” This article provides an updated overview of the diagnosis and management of tinea infections but reports no new clinical findings.
49 citations
,
July 2021 in “Nutrients” This review explores lifestyle modifications for women with polycystic ovary syndrome, discussing dietary, physical, and supplementation strategies, but reports no new clinical results.
47 citations
,
September 2023 in “Pharmacological Reports” In this review, researchers explored the roles of vitamins A, B3, C, D, and E in skin immunity, highlighting their potential as therapeutics for skin diseases due to their antioxidant, anti-inflammatory, and antimicrobial properties.
47 citations
,
September 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.
44 citations
,
October 2017 in “Journal of the American Academy of Dermatology” In this study, tofacitinib monotherapy was effective in achieving hair regrowth in over half of Korean patients with moderate-to-severe and refractory alopecia areata, though treatment discontinuation typically led to hair loss recurrence.
29 citations
,
July 2008 in “Journal of Cutaneous Pathology” This study found that follicular streamers are mostly present in non-scarring alopecia cases, and tracking their location can improve diagnosis accuracy.
25 citations
,
July 2021 in “Journal of Medical Virology” This review focuses on the various skin symptoms associated with COVID-19 but reports no new clinical findings.
22 citations
,
February 2010 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” This article reviews the evidence regarding the role of sex hormones in occult hyperadrenocorticism and reports no new findings, highlighting the unproven nature of their involvement.
21 citations
,
May 2005 in “Journal of the American Veterinary Medical Association” The exact cause of growth hormone-responsive alopecia in dogs is unclear.
19 citations
,
February 2013 in “The American Journal of Dermatopathology” This study found that follicular density and various hair growth ratios differ statistically between nonscarring and scarring alopecia, though significant overlap exists due to factors like sample size and scalp variation.
19 citations
,
August 2011 in “Archives of Dermatology” This abstract contains no research findings but is a snippet of a website interface for JAMA Dermatology.
16 citations
,
December 2016 in “Skin appendage disorders” This study analyzed patch test results to identify allergens causing scalp contact dermatitis, finding nickel, cobalt, and balsam of Peru among the most common in the patient population.
16 citations
,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses various aspects of hair color, including its formation and evolutionary variations, based on research presented at the 4th Intercontinental Meeting of Hair Research Societies 2004, without providing new experimental results.
15 citations
,
September 2005 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” This study found that trilostane treatment led to complete hair regrowth in three Alaskan malamutes with ACTH-stimulated elevated 17-hydroxyprogesterone levels within 6 months without any recognized adverse effects.
14 citations
,
November 2013 in “PloS one” This study found that transgenic mice overexpressing HGF/SF are more susceptible to UVA-induced melanoma, with melanin in the papillary dermis interacting with UVA to induce melanoma.
12 citations
,
May 2017 in “Medicine” This article provides an overview of acne vulgaris, discussing its causes, presentation, and psychosocial impact, but it reports no new research findings or clinical results.
12 citations
,
March 2016 in “Life Sciences” This review discusses the potential of combined therapy with WP 631 and epothilone B for ovarian cancer, but reports no new clinical results.
11 citations
,
February 2018 in “Archives of Pharmacal Research” This study found that finasteride decreases melanin levels in melanocyte and melanoma cells by inhibiting MC1R, without causing cytotoxicity, suggesting its potential role in regulating melanogenesis.
11 citations
,
December 2011 in “Revista Brasileira de Farmacognosia” In this animal study, petroleum ether and ethanolic extracts of Abrus precatorius seeds appeared to reverse androgen-induced alopecia in male albino rats by inhibiting the 5α-reductase enzyme, similar to finasteride.
11 citations
,
January 2006 in “Analytica Chimica Acta” Validated method reliably measures finasteride in tablets using liquid chromatography.
10 citations
,
March 2021 in “Pediatric dermatology” This article highlights that understanding cultural practices, empathetic patient communication, and social implications can enhance counseling and treatment for pediatric and adolescent patients with skin of color experiencing common dermatological issues like acne, atopic dermatitis, and traction alopecia.
10 citations
,
July 2014 in “Veterinary dermatology” This study found that deslorelin may promote hair regrowth in intact male dogs with hair cycle arrest, but had no effect on neutered females.
10 citations
,
November 2012 in “International Journal of Dermatology” This study identified that certain diseases, including AIDS and systemic lupus erythematosus, may cause African hair to change to a silky, wavy texture similar to neonatal hair in affected patients.
10 citations
,
February 2007 in “Clinical techniques in small animal practice” This review discusses the etiology and clinical findings of atypical hyperadrenocorticism in dogs due to sex steroid imbalance and explores various treatment options, but reports no new results.
9 citations
,
May 2013 in “JAMA Dermatology” This report documents two cases of eruptive nevi occurring in the skin folds of children with Langerhans cell histiocytosis.