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330-360 / 1000+ resultsresearch Influence of Liposomes and Niosomes on the In Vitro Permeation and Skin Retention of Finasteride
This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.
research Identification of Potential Cytochrome p450c 17 Alpha Inhibitors for the Treatment of PCOS via Scaffold Hopping and Fragment-Based De-Novo Drug Design
This study identified seven novel CYP17A1 inhibitor scaffolds as potential leads for treating polycystic ovary syndrome through an in silico approach, demonstrating favorable interactions, drug-like properties, and predicted bioactivities warranting further experimental validation.
research An Investigation of the Effects of Cationic Conditioning Systems on Hair Combability and Sensory Performance
This study found that cationic surfactant-based conditioning systems significantly reduce friction on hair fibers, improving wet and dry combability by forming a stable film layer on the hair’s surface, as verified by both instrumental and sensory evaluations.
research Structural studies of two solid steroid compounds
This study found that solid-state NMR combined with X-ray techniques provided critical insights into the structure and solvation of finasteride polymorphs, identifying gaps in existing patent characterizations.
research Polyherbal chocolate supplementation - a novel adjuvant therapy for polycystic ovary syndrome (PCOS)
This study developed a polyherbal chocolate formulation aimed at managing PCOS and hormonal balance, finding that formulation F2 showed excellent organoleptic properties and stability, with future in vivo studies being suggested.
research In-silico screening of potential anti-androgenic and anti-estrogenic phytocompounds from Saraca asoca for polycystic ovary syndrome treatment
This study identified procyanidin B2 and leucopelargonidin from Saraca asoca as potential inhibitors in PCOS by showing high binding energy scores against key enzymes involved in estrogen and testosterone biosynthesis.
research Tannic acid-modified MoS 2 /silk fibroin hydrogel photothermal antibacterial synergistic macrophage M2 polarization regulation for the treatment of diabetic ulcers
This study developed a multifunctional TA-MoS2-SF hydrogel for diabetic ulcer treatment, demonstrating enhanced photothermal bactericidal effects, immune environment remodeling, and fibroblast proliferation, suggesting it may serve as an effective 'antibacterial-immunomodulatory-repair' strategy.
research 26SCS-Loaded SilMA/Col Composite Sponge with Well-Arranged Layers Promotes Angiogenesis-Based Diabetic Wound Repair by Mediating Macrophage Inflammatory Response
The researchers reported that sulfated chitosan-containing sponges can modulate macrophage activity in diabetic wounds, reducing inflammation and promoting angiogenesis and tissue regeneration, which may enhance wound healing outcomes.
research Impact of substrate stiffness on dermal papilla aggregates in microgels
This study observed that dermal papilla cell aggregates showed increased viability and gene expression on softer 3D substrates, indicating the importance of substrate stiffness in cellular behavior.
research An Investigation of the Effects of Cationic Conditioning Systems on Hair Combability and Sensory Performance
This study found that cationic surfactant-based conditioning systems significantly improve hair combability by forming a stable low-friction film on hair surfaces, reducing friction and enhancing sensory performance compared to standard systems, as confirmed by both instrumental and sensory evaluations.
research A completely polyherbal conditioning and antioxidant shampoo: A phytochemical study and pharmaceutical evaluation
This study concluded that the formulated polyherbal shampoo is a chemical-free product with nourishing, conditioning, cleansing, and antimicrobial effects.
research Relative Influence of Ethanol and Propylene Glycol Cosolvents on Deposition of Minoxidil into the Skin
This study found that increasing the proportion of ethanol in minoxidil formulations improved skin penetration in both in vitro and in vivo tests on mice.
research Abnormalities in the hair morphology of patients with some but not all types of mucopolysaccharidoses
This study found that scanning electron microscopy revealed considerable abnormalities in hair morphology in MPS I, II, IIIA, and IIIB patients, potentially related to heparan sulfate accumulation.
research Development of a three‐point cantilever bending technique to study the mechanical properties of hair styling ingredients
This article provides guidelines and indices for a three-point cantilever bending test to measure mechanical properties of hair treated with both conventional and naturally-derived styling polymers, reporting no new experimental results.
research [Electrophoretic studies of acid mucopolysaccharides in skin, prekeratin of hair follicles and in keratoses of wool].
This study found that chondroitin sulfate levels were higher than hyaluronic acid in skin and hair follicle samples, with the highest concentration observed in prekeratin of hair follicles and wool fibers.
research Current advances of Dendrobium officinale polysaccharides in dermatology: a literature review
This review discusses the potential dermatological applications of Dendrobium officinale polysaccharides, noting their hair growth promoting, skin moisturizing, and antioxidant effects, but reports no new clinical results.
research Development and in vitro evaluation of liquid crystal-based polyherbal hair gels: physicochemical characterization, hair performance, and antioxidant assessment
This study found that the polyherbal gel formulations F4 and F6 demonstrated superior in vitro performance in hair care, showing promise as cosmeceutical candidates, although further in vivo and clinical studies are necessary to confirm their efficacy and safety.
research DEVELOPMENT OF THE EMULGE LFOR THE ANDROGENIC ALOPECIA TREATMENT
In this study, the researchers developed an optimal emulgel formulation for treating androgenic alopecia, determining that a base with 0.3% Carbomer Ultraz 10, 0.1% potassium sorbate, and 0.2% triethanolamine offered the best properties for drug release, application compliance, safety, and stability.
research The penetration, efficacy and potential of antiseptic nanoparticle-emulsions
This summary highlights in vitro and in vivo experiments showing that nano-sized liposomes with bound polihexanide penetrate hair follicles more effectively and may extend antiseptic effects longer than conventional polihexanide solutions.
research Colistin adorned topical nanoemulsion gel formulation for enhanced anti-microbial activity
This study reported that a colistin sulfate-loaded nanoemulgel showed improved antimicrobial activity and skin permeability compared to a CS solution, suggesting a potential new approach for treating severe infections caused by multidrug-resistant bacteria.
research Application of Polarisable Continuum Modelling to assess Minoxidil solubility in mixed solvents
This study investigated the solubility of minoxidil in various solvent mixtures and applied multiple models to understand solute-solvent interactions and energy dynamics.
research Highly flexible and controllable hierarchical MOF membrane for efficient drug release
research Tribological Properties between Taut Hair Fibers in Wet Conditions: A New Shampoo Formulation for Eliminating Stick‐Slip Friction
This study found that hair treated with shampoo containing water-soluble silicone demonstrated smoother sliding and better detangling, compared to shampoo with water-insoluble silicone, due to differences in conditioning film formation.
research Bioextracting Polyphenols from the Brown Seaweed Ascophyllum nodosum from Québec's North Shore Coastline
In this study, researchers found that the conventional solvent extraction method yielded the highest polyphenol content and antioxidant activity from Ascophyllum nodosum seaweed on Québec's North Shore.
research Green Surface Engineering of Spun-Bonded Nonwovens Using Polyphenol-Rich Berry Extracts for Bioactive and Functional Applications
This study developed a biodegradable nonwoven textile using a starch-based biopolymer and fruit extracts, resulting in materials that are stronger, more hydrophilic, and capable of releasing beneficial compounds over 72 hours, positioning them for potential use in medical, healthcare, and cosmetic applications.
research Encapsulation of Curcumin in Polystyrene-Based Nanoparticles—Drug Loading Capacity and Cytotoxicity
In this study, curcumin was efficiently loaded into PS–PAA nanoparticles at the formation stage, showing even distribution at low concentrations and good biocompatibility with human skin fibroblasts.
research Prevention of lipid loss from hair by surface and internal modification
This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups.
research Multifunctional Dynamic Cerium-Polypeptide Hydrogel with Antibacterial Antioxidative Antiinflammatory for Multidrug-Resistant Bacterial Infected Wound Healing
In this study, a cerium-polypeptide hydrogel was found to effectively treat MRSA-infected wounds by promoting faster wound repair and reducing inflammation compared to a standard hydrogel.
research Polymeric nanoparticles‐based topical delivery systems for the treatment of dermatological diseases
This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.