January 2019 in “ISGE series” The document concludes that effectively managing PCOS requires a multifaceted approach.
257 citations,
July 2018 in “Obstetrics & Gynecology” PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
6 citations,
May 2022 in “Frontiers in physiology” Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.
13 citations,
October 2011 in “Clinical Obstetrics and Gynecology” Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.
18 citations,
March 2014 in “Current Pharmaceutical Biotechnology” Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
96 citations,
February 2007 in “The Journal of Clinical Endocrinology & Metabolism” Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.
38 citations,
June 2004 in “Human Reproduction” The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
4 citations,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
48 citations,
January 2017 in “Skin Pharmacology and Physiology” Finasteride-loaded nanoparticles may help treat alopecia.
29 citations,
August 2008 in “Current Opinion in Pediatrics” Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.
12 citations,
January 2013 in “Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz” Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.
10 citations,
January 2009 in “Elsevier eBooks” Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
277 citations,
July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.
15 citations,
June 2015 in “Human Cell” Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
9 citations,
November 2009 in “Recent Patents on Drug Delivery & Formulation” Microemulsions could improve how drugs are delivered and absorbed in the body.
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
25 citations,
June 2011 in “International journal of pharmaceutics” Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
6 citations,
March 2023 in “Materials” The GNP crosslinked scaffold with antibacterial coating is effective for rapid wound healing and infection prevention.
10 citations,
July 2011 in “Springer eBooks” Carboxytherapy can improve skin conditions with few side effects, but results may vary and are not guaranteed.
34 citations,
July 2010 in “Expert Opinion on Drug Delivery” The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
47 citations,
July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics” Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
6 citations,
February 2023 in “Journal of nanobiotechnology” The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.
January 2025 in “AAPS PharmSciTech” Transethosomes improve drug delivery through the skin and show promise for treating various conditions.
1 citations,
November 2017 in “Dermatologic clinics” Combination therapies can improve hair loss treatment results and boost self-confidence in men.
66 citations,
August 1999 in “The Journal of Clinical Endocrinology & Metabolism” Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.
December 1989 in “The Journal of Dermatologic Surgery and Oncology” New techniques and findings in dermatologic surgery show improved pain management, safer liposuction, better hair transplantation, and effective treatments for skin conditions.