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This case report describes a 32-year-old Filipino female with mixed connective tissue disease who sequentially developed distinct autoimmune disorders over seven years, highlighting the complexities in diagnosis and management of overlap syndromes.

This study found that midazolam improved PTSD-associated behavioral deficits in rats through its action on the TSPO, CBR, and neurosteroidogenesis pathways.

In this study, men with previous finasteride use reported more severe sexual and psychological symptoms with greater cumulative exposure and older age, highlighting a need for further research on risk factors and long-term impacts.

This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.

This study suggests that prenatal genetic diagnosis of MELAS syndrome using amniotic cells may not reliably predict fetal outcomes due to phenotypic diversity observed in siblings with similar levels of mutant mtDNA.

This study found that finasteride impaired object recognition memory and altered hippocampal dendritic structures in male 3xTg-AD mice, suggesting potential sex differences in Alzheimer's disease pathology.

This study found that neonatal finasteride treatment in male rats altered hippocampal GABAA receptor subunit expression and led to increased anxiety-like behavior in response to progesterone in adulthood.

Older men's scalp damage increases with age and sun exposure, a baby girl in the Philippines has Schimmelpenning syndrome, and thyroid screening is advised for children with hair loss and certain risk factors.

This study found that neonatal administration of Allopregnanolone may mitigate some behavioral effects of early maternal separation in adolescence, but also lead to similar adverse effects as the separation in adulthood.

In this review, researchers provided a comprehensive analysis of anti-androgen therapies for polyendocrine metabolic ovarian syndrome (PMOS/PCOS), examining their efficacy and safety while proposing a phenotype-guided management framework and highlighting research gaps, such as long-term cardiovascular safety and predictive biomarkers.

This study found that among mother-infant pairs during the COVID-19 pandemic, lower maternal hair cortisol concentrations during pregnancy, combined with higher levels at six weeks postpartum, were associated with poorer infant developmental outcomes at six months.

This article highlights the health risks associated with adding paraphenylenediamine to mehndi, such as contact dermatitis and asthma, and emphasizes the need for regulatory checks as its use grows among cancer patients, women with alopecia, and pregnant individuals.

This report describes two cases where pemphigus lesions developed at sites of cosmetic procedures, suggesting these treatments might trigger the disease and should be distinguished from other post-surgery complications.

This case report describes a 34-year-old woman with pituitary stalk interruption syndrome, highlighting the need for long-term follow-up due to potential progression from isolated hormonal deficiencies to pan-hypopituitarism.

This dataset provides supplemental material for a study on long-term particulate matter exposure and androgenetic alopecia risk, including additional exposure data and sensitivity analyses, but reports no new clinical results.

This review explores disorders of sex development, emphasizing the need for a systematic, multidisciplinary approach and the benefits of genetic testing for better diagnosis and gender assignment planning, but it reports no new clinical findings.

This study developed and characterized new mouse models of Pemphigus that mimic different forms of the disease, but treatment with Methyl-Prednisolone showed only partial effectiveness.

The care model improved timely diagnosis and treatment for psoriasis and psoriatic arthritis.

This study found that coadministration of tadalafil and finasteride improved lower urinary tract symptoms and erectile function in men with benign prostatic hyperplasia better than finasteride alone over 26 weeks.

This study found that finasteride treatment in male rats has lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation, and gut microbiota composition even one month after discontinuation.

This case report describes a 7-year-old female from the Middle East with monilethrix, highlighting the disease's rarity in this population, characterized by brittle, sparse hair and keratosis pilaris.

This study found that PD-MSCs overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients, potentially offering a new therapeutic approach for degenerative diseases.

This review discusses the off-label use of SSRIs to manage inappropriate sexual behavior in elderly dementia patients and highlights the unclear risk of post-SSRI sexual dysfunction, noting a need for high-quality clinical trials.

This report describes a neurometabolic disorder linked to gain-of-function variants in the ODC1 gene, characterized by developmental delay, ectodermal abnormalities, and notable facial and neuroimaging features.

This correspondence discusses follicular mucinosis in association with pregnancy but does not report new clinical results, instead calling attention to the observed connection.

This study found that 20% of children initially diagnosed with premature pubarche were later identified with different clinical conditions during follow-up, highlighting the need for careful differential diagnosis over time.

This article reviews current understanding and management of peripheral arterial disease and reports no new results; the authors emphasize early diagnosis and lifestyle modification for better outcomes.

This report discusses the complex interplay between dermatological and psychiatric conditions and presents insights shared at the 22nd EADV Congress, but it reports no new research results.

This review examines primary and secondary immunodeficiencies, focusing on how healthcare providers can recognize and manage these conditions in children; it reports no new clinical results.