Persistent Sexual And Psychological Symptoms After Finasteride Discontinuation: A Cross-Sectional Observational Study

    April 2026 in “ Journal of Clinical Medicine ”
    Paweł Jędrzejczyk, Tomasz Ząbkowski, Jarosław Ratajski … Tomasz Syryło
    Studysummary In this study, men with previous finasteride use reported more severe sexual and psychological symptoms with greater cumulative exposure and older age, highlighting a need for further research on risk factors and long-term impacts.
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    Research cited in this study 10

    1. Multidimensional Assessment of Adverse Events of Finasteride: A Real-World Pharmacovigilance Analysis Based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024 PLoS ONE · 2025
    2. Post-Finasteride Syndrome: A True Clinical Entity? International Journal of Impotence Research · 2025
    3. Updated Review of Treatment of Androgenetic Alopecia Facial plastic surgery clinics of North America · 2024
    4. Use of 5-Alpha Reductase Inhibitors in Dermatology: A Narrative Review Dermatology and Therapy · 2023
    5. Penile Vascular Abnormalities in Young Men with Persistent Side Effects After Finasteride Use for the Treatment of Androgenic Alopecia Translational Andrology and Urology · 2020
    6. Post-Finasteride Syndrome: Risks and Side Effects of Finasteride for Androgenetic Alopecia Anais Brasileiros De Dermatologia · 2020
    7. Post-Finasteride Syndrome: An Emerging Clinical Problem Neurobiology of Stress · 2019
    8. Incidence of Type 2 Diabetes Mellitus in Men Receiving Steroid 5α-Reductase Inhibitors: Population-Based Cohort Study BMJ. British medical journal · 2019
    9. A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome Urology · 2018
    10. Sexual Dysfunction in Subjects Treated with Inhibitors of 5α-Reductase for Benign Prostatic Hyperplasia: A Comprehensive Review and Meta-Analysis International Journal of Andrology · 2017