Immunodeficiency Disorders: Evaluation and Management of Primary and Secondary Immunodeficiencies in Children
May 2019
in “
Pediatrics in review
”
TLDR People with primary immunodeficiencies often have frequent, severe, or unusual infections and may need special tests and management strategies.
The document discussed immunodeficiency disorders, highlighting that they were no longer considered rare. It emphasized that while susceptibility to infections was a well-recognized sign of primary immunodeficiencies (PIDs), some children presented with noninfectious symptoms that required evaluation by an immunologic specialist. The article reviewed both primary and secondary immunodeficiencies, focusing on the evaluation and management of children with PIDs. PIDs were described as inherent defects in immunity, mostly arising from genetic deviations, with over 300 identified types categorized into 9 clinical and immunologic phenotypes by experts.
