Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers identified significant signals indicating previously unrecognized risks of lipid metabolism abnormalities for several drugs, urging the need for better monitoring and label updates.

This study found that adjusting the polymer gel composition can create a more consistent release profile of finasteride with reduced initial burst release, enhancing patient compliance through in situ polymer precipitation.

This article discusses the FDA's decision not to approve 5α-reductase inhibitors for prostate cancer prevention, citing an increase in high-grade tumors but no mortality evidence, and reports no new results.

In this paper, three APS patients were followed over time, showing that the diagnosis and course of autoimmune polyglandular syndrome can evolve, highlighting the need for careful monitoring and potential re-evaluation.

PH-762 shows promise in treating skin cancer by effectively targeting and silencing PD-1 in tumors with minimal side effects.

This study found that short-term exposure to PM2.5 and Asian dust particles did not increase skin symptoms in schoolchildren.

This study found that biomimetic dermal papilla spheres cultured in a specific microenvironment can partially restore hair-inducing ability in high-passage dermal papilla cells in nude mice, resembling the characteristics of primary cells.

A dissolving microneedle patch with dutasteride offers effective, long-lasting hair loss treatment with fewer side effects.

This study aims to determine if an integrated early childhood development package can reduce developmental delays among two-year-old children in public health centers in Pakistan.

This study developed and optimized a molecularly imprinted polymer-based electrochemical sensor, demonstrating its ability to detect minoxidil with high sensitivity and selectivity at concentrations as low as 0.3 nM, and successfully applied it for minoxidil measurement in various real sample matrices.

Deep Brain Stimulation helps manage Parkinson's symptoms when medication isn't enough.

This study found that cyclic MPA is as effective as OCPs in resuming ovulation among women with PCOS, offering a viable alternative for those who cannot or choose not to use OCPs.

This study suggests that the 5α-reductase inhibitor finasteride modulates sensorimotor gating in rats by affecting D1 and D3 receptors, but not D2 receptors, with varying effects based on genetic strain.

This retrospective pharmacovigilance study reviewed adverse event reports from 2004 to 2025 for drugs treating benign prostatic hyperplasia, identifying distinct safety signals for α1-blockers, 5ARIs, and PDE5I, including some potential new adverse events that require further investigation.

This review discusses the clinical phenotypes of primary mitochondrial cytopathies linked to significant genetic defects in mitochondrial DNA, reporting no new clinical results; the authors emphasize the need for differential diagnosis.

Mycophenolic acid may help hair grow by activating pathways important for hair growth.

This study found that dissolving microneedle array patches containing mesoporous silica nanoparticles can deliver antigen-loaded nanoparticles into mice effectively, inducing strong immune responses similar to traditional subcutaneous injection.

In this study, researchers developed and validated a method to quantify pyrrolizidine alkaloids in honey and flour, increasing alkaloid recovery rates through successive extractions, achieving up to 86% recovery for honey and 76% for flour.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

This report describes a 60-year-old female with pretibial pruritic papular dermatitis who showed significant improvement of skin lesions after one month of treatment with oral pentoxifylline. The authors highlight the unique clinical and histological features of PPPD and propose pentoxifylline as a potential therapy.

This article discusses the role of external beam radiotherapy as a primary treatment method for cancer and reports no new clinical findings.

In this study, a single dose of PTH–CBD produced a sustained increase in bone mineral density for up to a year in mice, indicating its potential as an osteoporosis treatment.

This study found that adding PRP to DPCP treatment for severe alopecia areata did not enhance effectiveness compared to DPCP alone.

This study reports that 71% of patients treated with the gamma-secretase inhibitor PF-03084014 for desmoid tumors experienced dermatologic side effects, such as follicular lesions and pruritic eruptions, which were managed with topical or systemic treatments.

This review assessed patient-reported outcome measures for alopecia treatments but found that none met current FDA guidelines; however, some could potentially be adapted for more comprehensive use.

This study identified a new minoxidil analogue called triaminodil in an illegal hair-growth supplement, but no data on its chemical, toxicological, or pharmacological properties are available yet.

In this study, men with pre-diabetes seeking treatment for erectile dysfunction had worse hormonal and metabolic profiles and a higher risk of severe erectile dysfunction compared to those without pre-diabetes.

This study found that females exposed to high cumulative doses of cyproterone acetate had a 6–20 fold increased risk of developing meningiomas compared to those on lower doses.

This study found that Compound Diandao Pulvis Drug Facial Mask improved some signs of acne in a rabbit ear model, but its effects were not significantly different from tretinoin cream.