The Effects of Acute Finasteride Treatment in Dopamine Transporter Knockout Mice and MK-801-Treated Mice
October 2019
in “
Asian College of Neuropsychopharmacology
”
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6 / 1000+ resultscommunity Finasteride affects both 5a reductase and 5b reductase
6 upvotes 6 years ago Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.
community Massive study on finasteride side effects released
in Finasteride/Dutasteride 83 upvotes 3 years ago The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.
community Efficacy of different dutasteride doses vs finasteride
in Research/Science 123 upvotes 2 years ago Dutasteride doses matter for hair loss treatment and are more effective than finasteride. RU58841 is suggested for better gains, but side effect profiles should be considered.
community How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR?
in Finasteride/Dutasteride 22 upvotes 1 year ago Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.
community [study analysis] Microdose of topical Finasteride for all the benefits and none of the sides?
in Research/Science 104 upvotes 5 years ago Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.
community Comparing the effect of T suppression and DHT suppression
in Transgender 52 upvotes 1 year ago Trans women discuss using finasteride and dutasteride for hair loss and whether to continue after testosterone suppression. One user reduced dutasteride dosage after achieving undetectable testosterone levels.
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16 citations , October 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Dutasteride may protect the brain in early Parkinson's disease.