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Two studies in Cell Stem Cell reported that human and mouse somatic cells can be reprogrammed into induced pluripotent stem cells using microRNAs, eliminating the need for ectopic protein expression.

This study found that lipid extraction increased water diffusion in wool and hair fibers; the effect was more pronounced in hair, indicating lipids are crucial for water permeability.

This study found that somatosensory axons innervating Merkel cells in adult mouse skin exhibit significant plasticity, influenced by epithelial and neural factors, indicating a complex interaction in maintaining homeostasis.

This study reports that mutations in human L-PGDS affect the entrance and exit of ligands in its binding cavity, suggesting these residues play a role in ligand interaction processes.

The researchers reported that increasing protein content in human hair keratin/calcium alginate blend films led to larger molecular aggregates, which influenced the films' physical properties such as light transmittance and tensile strength.

This study observed that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments; linear filaments stabilize fused membranes, while branched filaments, connected by the protein Ezrin, drive integration, demonstrating actin's role in adapting to membrane biophysical changes.

In this study, researchers identified a recurrent MBTPS2 splice-site variant as a mutational hotspot in IFAP syndrome across diverse families, with phenotype severity suggesting the influence of additional modifiers.

In this study, AFM-based indentation was used to assess mechanical properties of murine skin wounds at two healing stages, revealing that early wounds exhibit stiffer hyperproliferative epithelium compared to granulation tissue, and highlighting significant influences of surface roughness on tissue stiffness measurements.

This study found that mature adipocytes can dedifferentiate into fibroblast-like cells, driven by PDGF and TGFβ signaling, which may play a role in wound repair and fibrosis.

This study used a probabilistic Boolean network model to explore hair follicle cell fate regulation and predicted that varying TGF-β levels, in coordination with BMP and TNF, can influence either apoptosis or cell proliferation during different follicle growth stages.

Tissue stiffness affects sweat gland development by guiding cell differentiation through specific signals.

This study introduced a novel method that uses upright structured illumination microscopy and atomic force microscopy to map the mechanical properties of thick living tissue slices, revealing the intricate mechanical heterogeneity of mouse skin and effects of preservation techniques on tissue stiffness.

This study analyzed the swelling behavior of human hair during permanent waving treatment, finding that both the microstructure and macrostructure of intermediate filaments swell simultaneously at the initial stage, and while partially destructed by reduction, they are considerably restored through oxidation.

In this study, the authors found that applying hypobaric pressure to the skin significantly increases the transdermal permeation of large molecules by enhancing diffusion, despite the associated skin stretching and hair follicle enlargement not fully explaining this effect.

This study introduced the dual-flow-RootChip platform to demonstrate that Arabidopsis roots exhibit non-autonomous adaptations, such as hair growth regulation, when subjected to varied environmental conditions on opposite sides.

In this study, a bioengineered construct using a biodegradable polycaprolactone mat cocultured with human keratinocyte and rabbit dermal fibroblast cells demonstrated potential as a tissue-engineered skin substitute, showing good cell adhesion and growth.

This study highlights the ZmNF-YC1-ZmAPRG pathway as a potential mechanism to improve maize tolerance to phosphorus deficiency, emphasizing its role in modulating lipid and photosynthetic activity, although direct impacts on root adaptations remain unclear (Bai et al., 2024).

Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.

This study demonstrated that the Turing bifurcation, typically a pitchfork bifurcation under zero-flux conditions, becomes transcritical under fixed boundary conditions, highlighting the importance of considering boundary condition variations in morphogenetic analyses.

This study suggests that increased amounts of less stable disulfide conformers in hair shafts may be linked to the brittleness observed in trichothiodystrophy.

This study used a probabilistic framework to show that platelet-rich plasma preparation results in significant variability in platelet dose due to factors like injected volume and concentration factor.

This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.

Polisorbate 20 is not suitable for curl creams due to instability.

In this study, researchers identified two significant genetic polymorphisms in the 3'-UTR of the HSP70 gene in Moa buffalo, which may play an important role in heat adaptation, providing insights for conservation and performance improvement in tropical climates.

This study found that treatment with mercuric acetate modifies the elastic properties of Lincoln wool fibers more rapidly than human hair, explaining the enhanced unshrinkable quality of wool under certain conditions.

This study suggests that translation levels may determine the proliferative potential of cultured human keratinocyte colonies, affecting their differentiation during epidermal maintenance and repair.

This research describes methods to analyze the mechanical properties and fracture characteristics of hair across different types and ages, using specialized tensile testing and imaging techniques, without reporting new results.

In this study, the researchers conducted tensile tests on individual curly human hair fibers sourced from a female donor and found distinct mechanical properties under various conditions, including different strain rates and temperatures, both dry and in saline immersion.

In this study, radial shockwave therapy significantly improved muscle spasticity, ankle range of motion, and functional abilities in children with spastic cerebral palsy, suggesting it may help them achieve greater autonomy in daily activities.

Keratin peptides can change hair shape gently without harsh chemicals.