Search

everythinglearnresearchcommunity

for

Search:↓

New method measures finasteride in plasma, finds two formulations bioequivalent.

Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.

Finasteride lowers scalp and blood DHT levels, potentially treating male-pattern baldness.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Researchers developed a method to measure plant compounds in rat blood and found they are quickly absorbed and eliminated within 36 hours.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Goat reproductive activity and coat growth are affected by light and temperature, with temperature altering prolactin levels and hair growth, but not melatonin or estrus onset.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Finasteride may lower cholesterol and slow heart disease progression.

Hair samples can reliably monitor tacrolimus levels in kidney transplant patients.

Method accurately measures finasteride in human plasma.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

PRP therapy with specific growth factors improves hair density and thickness in androgenic alopecia.

Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Men with low or no sperm count have lower salivary testosterone levels, and saliva testing can measure their testosterone well.

Topical aprepitant reduces skin rash and hair loss caused by cancer treatment.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

Finasteride's two formulations absorb similarly, showing bioequivalence.

GERD symptoms are linked to acid exposure time and daytime sleepiness, influenced by ghrelin levels.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

People with alopecia areata have higher levels of a heart disease marker than those without hair loss.

Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.

Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.