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The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

CD2 might be a new treatment target for patchy alopecia areata.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.

Fzd2 is important for skin and hair development through various signaling ways.

A patient with a rare hair condition and skin disorder showed hair improvement after treatment.

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.

A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.

A 37-year-old male with severe skin and internal issues has a rare inherited skin condition called dystrophic epidermolysis bullosa.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.

Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.

Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.

Understanding genetics is crucial for treating heart and skin diseases.

Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.

A boy's skin fragility and sparse hair were caused by a genetic mutation affecting skin cell adhesion.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Fatp4 is crucial for healthy skin development and function.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.