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The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

IL-1 alpha stops hair follicle growth and hair production.

Vitamin D3 is important for hair growth and protecting skin from damage caused by long-term sun exposure.

ALRV5XR effectively promotes hair regrowth in both men and women through different mechanisms.

CBD may help restore hair growth-related protein levels in alopecia caused by hormones or other factors.

Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.

New therapies are being developed that target integrin pathways to treat various diseases.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

COVID-19 patients often experience hair loss and scalp pain, which may be related to the severity of their infection and treatment drugs.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Desmoglein 4 is controlled by specific proteins that affect hair growth.

PRP injections can help increase hair density and thickness in men with hair loss.

Deoxyshikonin helps wounds heal faster in diabetic mice.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.

Vitamin D and calcium are important for skin stem cell function and wound healing.

Skin and nail problems like hair loss, dry skin, and fungal infections are common in people with long-term Type 2 Diabetes and can be prevented with good blood sugar control and foot care.