April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that GATA6 is a key regulator of the upper pilo-sebaceous unit homeostasis and differentiation in human skin.
January 2008 in “The Internet Journal of Plastic Surgery” Thorough cleaning and hair removal are essential to effectively treat and prevent recurrent pilonidal sinus.
78 citations
,
February 2004 in “British Journal of Dermatology” This article reviews the potential impact of melatonin on hair growth, noting its benefits observed in animals, but reports no clinical results in humans to date.
3 citations
,
December 2020 in “International Journal of Women's Dermatology” Scalp micro-wounding helps promote hair growth in female pattern hair loss.
September 2024 in “Journal of Cosmetic Dermatology” In this study, seven patients with refractory alopecia areata treated with concentrated growth factor and microneedling-assisted betamethasone experienced significant hair regrowth, with one achieving over 50% regrowth and six showing complete recovery, without adverse effects.
June 2024 in “Saudi Journal of Medicine” This study found that platelet-rich plasma therapy significantly increased hair diameter and density in male androgenetic alopecia patients over six months, particularly in those with AGA durations up to five years.
3 citations
,
July 2024 in “Dermatology and Therapy” The researchers reported that identifying specific hair shaft abnormalities is crucial for distinguishing patchy/plaque mycosis fungoides from psoriasis and eczematous dermatitis on non-scalp skin using dermoscopy.
October 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Using both minoxidil and finasteride together on the scalp works better for male hair loss than using either one alone.
April 2017 in “Journal of Investigative Dermatology” This study reports a new optimized protocol for isolating and labeling single cells from neonatal mouse skin, enabling high-quality single cell RNA sequencing for lineage-specific cell analysis.
2 citations
,
February 2024 in “Journal of the European Academy of Dermatology and Venereology” This study resulted in a draft version of the Patient‐Reported Impact of Dermatological Diseases measure, PRIDD, which includes 27 items refined from patient consensus and is now undergoing psychometric testing.
5 citations
,
May 2018 in “Drug Safety” This study found that using electronic healthcare record data can provide valuable early insights into the clinical context of about half of the new safety signals evaluated within a regulatory environment.
3 citations
,
April 2016 in “Journal of Investigative Dermatology” In this open-label trial, tofacitinib showed dramatic clinical responses in most patients with moderate-to-severe alopecia areata, supporting further research into JAK inhibitors for this condition.
August 2019 in “Journal of The American Academy of Dermatology” Platelet-rich plasma helps hair regrowth and improves quality of life in women with hair loss, but minoxidil may be more effective.
107 citations
,
August 2014 in “Dermatologic Surgery” This pilot study suggests injecting platelet-derived growth factors into the scalp may offer some clinical benefits for androgenetic alopecia, though further randomized trials are needed for confirmation.
48 citations
,
January 2018 in “Scientific Reports” This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.
23 citations
,
September 2020 in “Journal of Dermatological Science” This pilot study suggests that skin-resident γδT-cells may play a significant role in the early stages of alopecia areata pathogenesis, indicating a potential new target for therapeutic management.
23 citations
,
December 1988 in “British Journal of Dermatology” This pilot study suggests that topical cyclosporin may delay hair shedding and potentially treat alopecia, based on observations in a human scalp skin graft model on mice.
2 citations
,
April 2023 in “South East European Journal of Immunology” This pilot study found elevated levels of leptin and other proinflammatory molecules in the serum of melanoma patients, suggesting a potential role for leptin in melanoma progression and a possibility for targeting it in adjuvant therapy.
2 citations
,
March 2021 in “Journal of Cosmetic Dermatology” This pilot study found that among male androgenetic alopecia patients, 2.5 mg oral minoxidil with platelet-rich plasma led to higher patient satisfaction than 1.25 mg, though hair count improvements were not statistically significant.
2 citations
,
January 2021 in “Journal of The American Academy of Dermatology” This pilot study found that examining changes in scalp scales after scraping may effectively distinguish seborrheic dermatitis associated with androgenetic alopecia from fibrosing alopecia in a pattern distribution.
April 2026 in “Journal of Craniofacial Surgery” This pilot study found that plasma- and sonophoresis-assisted delivery of an exosome-containing formulation improved hair and scalp metrics over 12 weeks, with short-term safety observed, but controlled trials are needed for confirmation.
December 2025 in “Journal of Forensic Sciences” This pilot study found that prebleaching either virgin or previously colored hair only slightly affects the SERS spectra of dyes applied afterward, without impacting the accuracy of dye identification, supporting the technique's robustness for forensic analysis of hair dyes.
April 2023 in “Tikrit journal of pharmaceutical sciences” This pilot study found that ginger may improve hair growth and allow for a reduction in prednisolone dosage by mitigating oxidative stress in patients with alopecia areata over 60 days.
November 2022 in “Journal of Investigative Dermatology” This pilot study suggests that lovastatin may counteract stress-induced MICA expression in hair follicles and enhance MICA shedding, potentially offering a complementary approach for alopecia areata treatment.
This pilot study found that Optical Coherence Tomography can non-invasively resolve hair follicle density and hair shaft and follicle diameters in patients at varying stages of hair loss.
27 citations
,
January 2005 in “American Journal of Clinical Dermatology” This pilot study found that azelaic acid treatment for patchy alopecia areata had similar hair regrowth results as anthralin, suggesting it may be an effective topical therapy.
15 citations
,
August 2022 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” This pilot study found that intraovarian platelet-rich plasma administration significantly improved the euploidy rate of embryos in infertile women with previous IVF failures.
9 citations
,
January 2014 in “Dermatology online journal” This pilot study evaluated bimatoprost ophthalmic solution 0.03% for eyebrow hair regrowth in ten female patients, but reports no new clinical results.
8 citations
,
March 2023 in “BMC Research Notes” This pilot study explored a new method using laser-capture microdissection and 16S rRNA gene sequencing to analyze the human scalp hair follicle microbiome more accurately, revealing region-specific variations in microbial diversity and abundance.
4 citations
,
June 2003 in “Fertility and Sterility” In this pilot study, finasteride increased testosterone/dihydrotestosterone and progesterone/dihydroprogesterone ratios in normal ovulatory women but did not alter ovulation or gonadotropin secretion.