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New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

Improved understanding of stem cell mechanisms can enhance skin tissue engineering.

DHT, a testosterone byproduct, causes male pattern baldness.

Home-use lasers and IPL devices are unlikely to directly cause paradoxical hair growth; it may be linked to inflammation or hormonal issues.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Msx2 and Foxn1 are both crucial for hair growth and health.

Hair transplantation between identical twins can successfully treat severe, nonprogressive hair loss due to follicular aplasia.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

The document is a detailed medical reference on skin and genetic disorders.

Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

Improving the environment and cell interactions is key for creating human hair in the lab.

Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Hair follicle regeneration possible, more research needed.

Povidone iodine reduced skin bacteria more than chlorhexidine gluconate, but neither met FDA reduction standards.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.

Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Higher sebum levels are linked to more severe male baldness.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.