December 2024 in “Varna Medical Forum” This article reviews scientific literature on the properties of essential oils and herbs in cosmetic medicine, highlighting their antimicrobial, anti-inflammatory, and antioxidant benefits in skin and hair care and their potential as natural alternatives to synthetic cosmeceutical ingredients for promoting dermatological health.
This study investigated the effects of a YH complex, derived from Cinnamomum cassia and Astragalus membranaceus, on androgenetic alopecia in mice, finding that it promoted hair regrowth and improved hair follicle health by modulating hair cycle regulation and reducing apoptosis signaling pathways.
January 2024 in “Biological & clinical sciences research journal” This review of 355 articles found that apigenin, a compound found in many plants and vegetables, is mainly researched for its anti-inflammatory, neuroprotective, and anti-cancer properties, with enhanced efficacy when combined with allopathic drugs.
25 citations
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May 2016 in “Molecular biology of the cell” This study found that the AtSfh1 protein in Arabidopsis is essential for phosphatidylinositol-4,5-bisphosphate signaling crucial to polarized root hair growth, utilizing both phosphatidylinositol and phosphatidylcholine-binding activities.
November 2025 in “PLoS ONE” This study found that synthetic RNA and DNA trigger significant increases in certain chemokines in human keratinocytes, predominantly via NF-κB activation, without evidence of alternative splicing, suggesting other regulatory pathways may be involved.
March 2026 in “Food Science & Nutrition” In this study, high-dose Arachis hypogaea root extract significantly reduced prostate weight and markers of glandular hyperplasia in testosterone-induced BPH in mice, with associated changes in inflammatory gene expression and beneficial shifts in gut microbiota.
53 citations
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January 2017 in “BioMed research international” This review discusses the importance of omega-3 fatty acids for human health and explores recent advancements in genetically modifying plants to produce these essential nutrients, but reports no new results.
August 2026 in “Journal of Drug Delivery Science and Technology”
March 2014 in “Journal of The American Academy of Dermatology” A botanical extract may help manage hair loss from chemotherapy by preventing cell death in hair follicles.
23 citations
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October 1996 in “Dermatologic clinics” This review discusses genomic and postgenomic alterations in chronic degenerative diseases and potential modulation by dietary and pharmacological agents, reporting no new clinical results.
10 citations
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April 2022 in “Critical reviews in food science and nutrition” This review examines the potential role of odorant receptors in human skin cells responding to flavor compounds and their implications for skin health and disease, without providing new clinical results.
10 citations
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January 2022 in “Journal of Research in Pharmacy” In this experimental study on Wistar albino rats, Cotinus coggygria leaf extract demonstrated potential as a treatment for burn-induced skin damage by reducing cytokine levels and promoting tissue healing.
September 2024 in “International Journal For Multidisciplinary Research” This study highlights the significant pharmacological potential of Tridax procumbens, a plant with various therapeutic properties such as liver protection, immune modulation, and wound healing, though it notes that more research is needed to identify its active compounds and mechanisms for drug discovery.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review suggests that curcumin and piperine may offer a promising multi-target therapeutic approach for alopecia by simultaneously modulating androgenic and inflammatory pathways, though experimental and clinical validation are necessary to confirm their efficacy.
16 citations
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July 2020 in “Advances in Traditional Medicine” This study found that the combined ethanolic extract ethosome formulation of Phyllanthus niruri, Zingiber officianale, and Croton tiglium Linné showed better safety and less cytotoxicity for hair growth promotion compared to the petroleum ether formulations.
This review discusses the use of medicinal plants for combating and preventing alopecia but reports no clinical results, emphasizing the presence of plant-based cosmetics on the market.
3 citations
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June 2024 in “Immunopharmacology and Immunotoxicology” This study found that cardamonin can reduce inflammation in TNF-α-stimulated human periodontal ligament cells by suppressing specific cytokines and chemokines and inhibiting key inflammatory signaling pathways.
This chapter reviews nanocarriers for acne therapy, highlighting their ability to reduce lesions and inflammation while improving the safety and effectiveness of treatment, though no new clinical results are reported.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlighted the potential benefits of herbal hair oils as a natural alternative to synthetic hair care products, noting that a traditionally prepared formulation demonstrated favorable physicochemical properties and no skin irritation, while promoting healthy hair and scalp.
10 citations
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January 2011 in “Skin research and technology” This study found that procyanidin oligomers bind to keratin and inhibit oxidative hair damage, suggesting their potential use in protective hair care products.
1 citations
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January 2006 in “Maia-rivista Di Letterature Classiche” This review discusses the bioactive compounds and biological activities of Polygonum multiflorum Thunb. and highlights concerns about its hepatotoxicity, but reports no new clinical results.
May 2026 in “Phytomedicine”
March 2012 in “Daehan hwajangpum hakoeji/Daehan hwa'jangpum haghoeji” This study observed that a cream containing functional compounds from medicinal plants increased collagen production in human skin, while a hair tonic enhanced hair growth in mice.
In this review, researchers evaluated 111 studies on the biological activities and phytochemical components of the plant Tridax procumbens, emphasizing its ethnobotanical potential and the need for more research to understand its therapeutic benefits, especially in its native tropical regions.
8 citations
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July 1977 in “Lipids” This study found a negative correlation between dietary monoene levels, particularly oleic acid, and the capacity for PGE₂ synthesis in rat skin, with the most severe skin issues noted in those fed Zephyr rapeseed oil.
June 2026 in “International Journal of Drug Delivery Technology” In this study, researchers developed a polyherbal hair growth oil using botanical substances and base oils like coconut and castor oil, finding it to be stable, non-irritating, and suggesting potential hair-growing properties through mechanisms such as scalp blood flow improvement and anti-inflammatory effects.
October 2025 in “Quantum Journal of Medical and Health Sciences” This review outlines the phytochemical composition and pharmacological potential of Tridax procumbens, a plant traditionally used in various regions for its purported medical benefits, including antioxidant, antimicrobial, and anti-inflammatory effects, among others.
December 2024 in “Frontiers in Pharmacology” In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.
January 2025 in “ARC Journal of Dermatology” In this study, exposure to e-cigarette vapor was reported to trigger the release of proinflammatory cytokines IL-6, IL-8, and IL-10, which could contribute to dermatological issues.
August 2011 in “Planta Medica” This study suggests that the hair growth-promoting effects of 4-O-methylhonokiol may be linked to its ability to modulate TGF-β-induced cell cycle arrest and oxidative stress in HaCaT cells.