research Gender Differences in Cardiac Hypertrophy
Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
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research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Epigenetic Regulation in Adult Stem Cells and Cancers
Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research AKR1D1 Regulates Glucocorticoid Availability and Glucocorticoid Receptor Activation in Human Hepatoma Cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
research Nutrition Interventions for Obesity
Eating less and exercising more, with personalized diet plans and realistic goals, can lead to weight loss and better health, but more research is needed for long-term success.
research Transcriptomic Profiling in Silurana Tropicalis Testes Exposed to Finasteride
Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
research Increased 25(OH)D3 Level in Redheaded People: Could Redheadedness Be an Adaptation to Temperate Climate?
Redheaded people may have evolved to efficiently make vitamin D in areas with less sunlight.
research Testicular Steroidogenesis: Production and Regulation of Testosterone and Dihydrotestosterone
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Potential Efficiency of Antioxidants to Prevent Pressure Ulcers: A Neglected Hypothesis
Antioxidants might help prevent pressure ulcers, but more research is needed to find effective ones.
research Gonadal Sex Steroids: Production, Action, and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research Molecular Basis of Maintaining Circannual Rhythm in the Skin of Cashmere Goat
Goat skin changes with the seasons due to genes affected by daylight and hormones.
research Illuminating Microflora: Shedding Light on the Potential of Blue Light to Modulate the Cutaneous Microbiome
Blue light might help treat skin conditions by affecting the skin's bacteria.
research Human and Animal Cells Under Influence of Different Lighting and Stimuli
Different light affects cell functions and can help treat skin conditions.
research Greasy Hair Against Obesity: TSLP-Induced Sebum Production Reduces Fat
Increasing sebum production might help reduce fat and improve metabolism.
research Zinc in the Soil and Its Importance for Plants and Human Health: An Integrated Review
Zinc is essential for plant growth and human health, but many soils lack enough zinc, affecting crops and potentially leading to health problems.
research A Missense Mutation in Lama3 Causes Androgen Alopecia
A gene mutation in Lama3 is linked to a common type of hair loss.
research Revisiting the Role of Melatonin in Human Melanocyte Physiology: A Skin Context Perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research A Novel Actor in Skin Biology: The Mineralocorticoid Receptor
Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.
research Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures
Skin cysts might help advance stem cell treatments to repair skin.
research The Tale of Stress: An Exploratory Analysis of Cortisol Levels in the Tail Hair of Captive Asian Elephants
Elephant tail-hair can show past stress levels, matching times when stressful events happened.
research The Effects of Intradermal Injections of Spermidine on the Growth Rate of Fibers and Mitosis of Wool Follicles in Merino Lambs
Spermidine injections increased wool growth rate in lambs without changing fibre thickness.
research Epidermal Stem Cell Lineages: Roles in Skin Integrity, Stress Response, and Disease
Epidermal stem cells are crucial for skin health and problems with them can cause issues like poor wound healing, cancer, and aging.
research Characterization of Type II Rickets Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor
The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
research Reversible Activation of c-Myc in Skin
Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
research Type XVII Collagen Coordinates Proliferation in the Interfollicular Epidermis
Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
research The Role of the Microbiome in Scalp Hair Follicle Biology and Disease
The scalp's microorganisms significantly affect hair health and disease.
research Macrophage Ferroportin Is Essential for Stromal Cell Proliferation in Wound Healing
Macrophage iron release is crucial for hair growth and wound healing.
research Mechanisms Involved in the Relationship Between Vitamin D and Insulin Resistance: Impact on Clinical Practice
Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.
research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.