May 2026 in “Journal of Drugs in Dermatology” New topical treatments and methods can help manage female pattern hair loss.
January 2020 in “Journal of clinical and cosmetic dermatology” This article reviews the etiology of FPHL, distinguishing between androgen-dependent and androgen-independent forms, but reports no new clinical findings; it highlights the need to better understand its pathogenesis.
7 citations
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January 2019 in “Australasian Journal of Dermatology” In this study, the CYP 21A2 gene p.V281L mutation was associated with an increased susceptibility to familial frontal fibrosing alopecia, suggesting an antigen-driven mechanism linked to certain human leukocyte antigen haplotypes.
72 citations
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November 2012 in “PloS one” This study found that dysregulation of the folliculin-p0071 interaction may lead to changes in cell adhesion and signaling, contributing to conditions like emphysema and renal cell carcinoma.
October 2024 in “Stem Cell Research & Therapy” This study found that CGF may be effective in reducing inflammation and improving skin conditions in psoriasis, particularly in patients resistant to other treatments.
45 citations
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May 2022 in “Biomedicines” This review discusses using human follicular fluid in metabolomic analysis as a diagnostic tool and predictor of success in assisted reproductive technology for PCOS patients, reporting no new results.
20 citations
,
January 2017 in “Scientific reports” This study found that cetaceans have adapted their fibroblast growth factors to assist in low bone density, hypoxia tolerance, and the development of rigid flippers, reflecting significant evolutionary changes for aquatic life.
24 citations
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November 2013 in “Molecular Medicine Reports” This study demonstrated that human hair follicle stem cells can be efficiently differentiated into endothelial-like cells using VEGF and bFGF, suggesting their potential as a novel cell source for vascular tissue engineering.
91 citations
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August 2015 in “Anais Brasileiros De Dermatologia” This review discusses the clinical, epidemiological, and pathophysiological aspects of female pattern hair loss, reporting no new research findings.
6 citations
,
January 2017 in “British Journal of Dermatology” This article reviews frontal fibrosing alopecia, exploring its characteristics, demographics, and associated conditions, and calls for controlled trials due to an increase in worldwide cases; it reports no new findings.
3 citations
,
December 2024 in “Journal of Animal Physiology and Animal Nutrition” In this study, researchers found that reducing FGF20 expression in dermal papilla cells of fine-wool sheep impedes the growth and differentiation of hair follicle stem cells, providing insights into wool trait improvement and regenerative medicine applications.
42 citations
,
September 2007 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.
24 citations
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January 2018 in “Development” This study found that Frizzled genes Fzd3 and Fzd6 are redundantly involved in controlling hair follicle polarity in mice, but operate through distinct mechanisms, highlighting their complex role in hair orientation.
July 2018 in “European Medical Journal” This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.
December 2021 in “Journal of pharmaceutical research international” This study found that trichoscopy can effectively differentiate female pattern hair loss from chronic telogen effluvium based on specific features like hair shaft diameter variability and density differences, aiding in targeted treatment planning.
November 2022 in “Journal of Investigative Dermatology” This study generated a transcriptomic map of human hair follicle compartments, providing a database for identifying compartment-specific gene expression which may aid in developing targeted treatments for hair follicle disorders.
1 citations
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April 2017 in “Journal of Investigative Dermatology” In this study, D-OCT imaging revealed distinct structural and vascular changes in patients with frontal fibrosing alopecia, highlighting the technique's potential for diagnosing and monitoring the condition's activity.
January 1982 in “Clinical Cosmetic and Investigational Dermatology” This case report describes a 54-year-old woman with familial dyskeratotic comedones who experienced slight improvement in her skin lesions after three months of treatment with topical retinoids and urea cream.
2 citations
,
January 2008 in “Journal of Society of Cosmetic Chemists of Japan” PMS nanoparticles improve damaged hair by protecting and restoring its surface and color.
3 citations
,
December 2024 in “Stem Cell Reports” In this study, researchers observed that low levels of fucose-binding lectin staining characterize limbal epithelial progenitor cells, which maintain a high proliferative capacity and may be enhanced by inhibiting fucosylation, offering insights for regenerative therapy of the limbal stem cell niche.
19 citations
,
April 2013 in “Drug Development and Industrial Pharmacy” This study highlights the significance of the hf pathway for the skin permeation of ionized and hydrophilic high molecular compounds, and the usefulness of hf-plugging in evaluating their skin permeability.
73 citations
,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This article reviews the potential relationship between different forms of permanent hair loss such as cicatricial pattern hair loss and discusses related conditions, reporting no new clinical findings.
January 2024 in “Indian Journal of Dermatology” This study found that women with FPHL may have an increased cardiovascular risk, as indicated by associations with metabolic syndrome, insulin resistance, and elevated biochemical markers.
11 citations
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June 2010 in “Medical Molecular Morphology” April 2026 in “Journal of Dermatological Treatment” This study concluded that in female pattern hair loss patients, CGF and i-PRF treatments were more effective than PRP in increasing target area hair count, with i-PRF having the lowest adverse event rate.
November 2022 in “Research Square (Research Square)” This meta-analysis suggests a significant association between the use of facial sunscreen and moisturizer and frontal fibrosing alopecia, while finding no significant relationship with hair products or treatments.
January 2011 in “Journal of Diagnosis and Therapy on Dermato-venereology” This study found that female pattern hair loss may be influenced by genetic factors and hormonal changes, particularly in young adults, and identified specific dermoscopic features associated with the condition.
7 citations
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May 2019 in “Journal of the Formosan Medical Association” This study found that overweight women with polycystic ovary syndrome carrying the HSD3B1 1245C allele had an increased presence of female pattern hair loss compared to those with the wild-type genotype.
2 citations
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June 2024 in “Frontiers in Plant Science” This study found that RALF peptides, through liquid-liquid phase separation, form condensates with pectin and other proteins, playing a pivotal role in plant development and stress response regulation.
August 2022 in “Nutrients” This ex vivo study found that hair follicles in female pattern hair loss exhibited nutrient insufficiency and dormant metabolism, but maintained nutrient uptake capability, suggesting potential benefits of nutritional supplementation as an adjunct therapy.