72 citations
,
November 2012 in “PloS one” This study found that dysregulation of the folliculin-p0071 interaction may lead to changes in cell adhesion and signaling, contributing to conditions like emphysema and renal cell carcinoma.
60 citations
,
May 2018 in “Indian Journal of Psychological Medicine” This article highlights the lack of attention to the impact of polycystic ovarian syndrome on women's identity, mental health, and quality of life in India without offering new findings.
53 citations
,
September 2020 in “Stem Cell Research & Therapy” This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.
42 citations
,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers identified two distinct homozygous mutations in the KRT85 gene among consanguineous Pakistani families with pure hair and nail ectodermal dysplasia, highlighting variations in severity and potential impacts on the K85 protein function.
40 citations
,
January 2010 in “Annales D Endocrinologie” This article discusses diagnostic guidelines for PCOS, emphasizing the use of the Rotterdam criteria and recommending clomiphene citrate as the first-line treatment for ovulation induction; it reports no new clinical results.
36 citations
,
August 2021 in “Nature Cell Biology” This review discusses the potential of organoids in modeling COVID-19 disease and developing therapies, without reporting new results, and highlights opportunities and challenges in their application for research.
33 citations
,
January 2018 in “International Journal of Biological Sciences” This study demonstrates the use of the CRISPR-Cas9 system to successfully edit the EDAR gene in Cashmere goats, resulting in goats with distinct hair follicle characteristics.
31 citations
,
March 2018 in “Frontiers in Immunology” This article reviews the complexities and challenges in classifying systemic lupus erythematosus and the problematic role of the anti-dsDNA antibody as a biomarker, without presenting new experimental findings.
29 citations
,
January 2011 in “Journal of Obstetrics and Gynaecology” This review discusses insulin resistance in women with polycystic ovary syndrome and reports no new clinical results; it highlights the potential benefits of lifestyle changes and insulin-sensitizing drugs.
26 citations
,
June 2014 in “Fertility and Sterility” In this study, normal weight adolescents with PCOS showed increased insulin resistance and significantly lower levels of high molecular weight adiponectin compared to controls, despite no other metabolic differences.
24 citations
,
June 2018 in “Reviews in endocrine and metabolic disorders” This review discusses the epidemiology, clinical manifestations, and pathogenesis of autoimmune skin diseases and their associations with thyroid diseases, reporting no new clinical results.
24 citations
,
January 2008 in “KARGER eBooks” This review discusses recent advances in understanding the pathogenesis of autoimmune alopecia areata and reports no new clinical results; it highlights potential for developing more effective treatments.
20 citations
,
June 2010 in “International Journal of Dermatology” In this study, acne and hirsutism in women were associated with a higher prevalence of polycystic ovary syndrome compared to those without these conditions.
18 citations
,
January 2015 in “Data series” This report describes a study of estuarine bed-sediment quality in New Jersey and New York post-Hurricane Sandy, focusing on contamination extent and potential long-term impacts, with no new findings included.
17 citations
,
December 2019 in “Stem Cells International” This review examines the recent progress in using bioactive molecules for skin regenerative medicine and reports no new clinical results; the authors suggest this method could become a promising strategy for in situ skin regeneration.
13 citations
,
April 2023 in “Nature communications” In this study, researchers used EHR data from two large PCORnet networks to identify a range of long COVID diagnoses, highlighting varying post-acute risks across populations in NYC and Florida.
11 citations
,
July 2014 in “Gene” This study reports a unique case of common variable immunodeficiency with autoimmunity linked to a heterozygous S250C variant in the autoimmune regulator gene, suggesting a potential molecular basis for this combination.
11 citations
,
January 2012 in “International Journal of Endocrinology” In this study, the prevalence of insulin resistance in reproductive-aged Thai women with polycystic ovary syndrome was found to be 20%, with age, waist circumference, acanthosis nigricans, and dyslipidemia as significant predictors.
10 citations
,
April 2020 in “Clinics in Dermatology” This case report describes a girl in China with biotinidase deficiency confirmed by genetic mutations, whose skin and hair symptoms improved with biotin therapy.
10 citations
,
March 2019 in “Human Genetics” This study identified a genetic variant in the SGK3 gene related to hairlessness in Scottish Deerhounds, suggesting a similar role for androgen-independent hair loss in humans.
9 citations
,
March 2018 in “European journal of dermatology/EJD. European journal of dermatology” This study in a Pakistani family identified a novel ST14 gene variant as the likely genetic cause of autosomal recessive ichthyosis with hypotrichosis syndrome.
9 citations
,
November 2016 in “Journal of medical science and clinical research” In this study, the prevalence of clinical polycystic ovary syndrome among high school girls in Sambalpur, Odisha, was found to be 12%.
8 citations
,
January 2023 in “Journal of Clinical and Translational Hepatology” This study examines the development and application of cultured models for gallbladder carcinoma and highlights innovations and challenges in constructing effective in vitro growth models for cancer research.
7 citations
,
April 2011 in “Expert review of dermatology” This article reviews practical approaches for managing dermatologic conditions in patients with skin of color and reports no new clinical findings.
5 citations
,
January 2024 in “American Journal of Translational Research” This research highlighted that the gut microbiota may influence ovarian health, suggesting it could be used as a biomarker for early diagnosis and treatment of diseases like PCOS, ovarian insufficiency, and ovarian cancer due to its impact on hormone levels.
5 citations
,
May 2011 in “European Journal of Medical Genetics” This case report describes a 44-year-old patient with late-onset partial lipodystrophy, mental retardation, epilepsy, ichthyosis, and glomerulonephritis, linked to a 10 Mb duplication of chromosome region 5q31.3-5q32.1.
3 citations
,
April 2019 in “Journal of psychosexual health” This review discusses the psychiatric and sexual comorbidities of PCOS, emphasizing the need for a multidisciplinary approach to manage sexual dysfunction due to high prevalence rates found in recent studies.
2 citations
,
September 2015 in “Clínica e Investigación en Arteriosclerosis” This review discusses the association between certain dermatological diseases and increased cardiovascular risk, highlighting the need for clinicians to address cardiovascular risk factors in these patients.
1 citations
,
January 2022 in “Research Square (Research Square)” This study found that CRISPR/Cas9 efficiently edited two cellulose synthase-like genes in spinach, significantly altering root hair growth patterns and suggesting potential for large-scale genome editing in this crop.
1 citations
,
October 1990 in “The Lancet” Using minoxidil for hair growth may cause skin lesions in some people, and taking breaks from nitrate patches for angina might worsen symptoms.