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Melatonin directly affects mouse hair follicles and may influence hair growth.

Higher leptin levels link to hair loss.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

A mother's diet at conception can cause lasting genetic changes in her child.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

New effective scar treatments are urgently needed due to the current options' limited success.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

The EDAR gene greatly affects hair thickness in Asian populations.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

Having enough iron improves the effectiveness of a specific hair loss treatment in women.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Aromatase gene variation may increase female hair loss risk.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.