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Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.

There are many treatments for common hair loss, but more trials are needed to decide which are best.

Topical JAK inhibitors may help treat alopecia universalis by promoting hair regrowth.

Biologics, especially Dupilumab, are effective and safe for treating severe childhood eczema.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

New oral treatment, finasteride, effectively and safely treats common hair loss.

JAK inhibitors help hair regrowth in alopecia areata but have a high risk of side effects.

Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.

Topical treatments for hair loss can be effective but need careful safety evaluation.

Bleach baths with 0.005% hypochlorite help manage atopic dermatitis by affecting skin cells and reducing itchiness.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Using skin stem cells and certain molecules might lead to scar-free skin healing.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

New regenerative therapies show promise for treating hair loss.

More precise, personalized therapies are needed for autoimmune diseases.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

The document concludes that there is hope for future psychopharmacology research despite challenges in treating schizophrenia.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Dermatologists should customize cosmetic treatments for dark-skinned patients to minimize risks and complications.

Reliable method detects finasteride in human plasma at low doses.

Hair loss in men treated best with early medication or transplant, new treatments researched.