65 citations
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February 2011 in “Molecular cancer therapeutics” CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.
505 citations
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December 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
7 citations
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November 2022 in “Toxics” The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.
1 citations
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June 2023 in “Nutrients” Vitamin D deficiency is linked to a higher chance of metabolic syndrome in women with PCOS.
115 citations
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September 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
9 citations
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March 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
189 citations
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July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
142 citations
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March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
6 citations
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May 2022 in “Biomedicine & pharmacotherapy” Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
1 citations
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April 2022 in “Journal of Ayurveda and integrative medicine” Blumea eriantha DC extract shows strong potential for promoting hair growth.
1 citations
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January 2018 in “Molecular and integrative toxicology” Getting the right amount of selenium is important for health; too little can cause disease, and too much can lead to toxicity.
March 2024 in “Regenerative therapy” miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
June 2023 in “IntechOpen eBooks” Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
68 citations
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January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
50 citations
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January 2014 in “PLOS ONE” Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
23 citations
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November 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Tailored treatments for alopecia areata are recommended based on severity and patient needs.
21 citations
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July 2022 in “Orphanet journal of rare diseases” New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
18 citations
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October 2020 in “Radiation Research” Some drugs may help treat both COVID-19 and radiation injury.
9 citations
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March 2022 in “Frontiers in Immunology” Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
6 citations
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January 2018 in “Advances in experimental medicine and biology” Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
4 citations
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February 2018 in “World journal of surgical oncology” A young woman with kidney cancer experienced rare hair loss from a cancer drug and unusual cancer spread, suggesting early drug treatment might reduce spread and prolong survival.
1 citations
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January 2022 in “Journal of Biosciences and Medicines” Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
1 citations
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December 2021 in “Androgens” Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
February 2024 in “Pharmaceutics” Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.
May 2022 in “Maǧallaẗ Buḥūṯ Al-Tarbiyyaẗ Al-Nawʿiyyaẗ (Print)” Eating a high inositol diet significantly improves insulin resistance and hormone levels in women with PCOS.
January 2023 in “International Journal of Pharmaceutics”
113 citations
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June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
70 citations
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September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
54 citations
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January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.