2 citations
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January 2015 in “BioMed Research International” This article reviews various aspects of growth factor research, highlighting their role in treatments and emphasizing the need for further clinical trials to validate their efficacy in biomedical applications.
This review found that 5α-reductase inhibitors (such as finasteride and dutasteride) effectively reduce prostate size and stabilize hair loss but are associated with sexual dysfunction; they remain essential treatments for BPH and androgenic alopecia, requiring tailored risk-benefit assessments.
This review analyzed clinical trials and guidelines on 5-α-reductase inhibitors (5-ARIs) and found these drugs significantly improve urinary symptoms in BPH and stabilize hair loss in androgenic alopecia, but may cause sexual dysfunction and gynecomastia.
July 2025 in “Saudi Journal of Medicine and Public Health” In this review, 5α-reductase inhibitors like finasteride and dutasteride were found to significantly reduce prostate volume and stabilize hair loss, but they also carry risks of sexual dysfunction, necessitating careful patient evaluation and monitoring.
July 2024 in “Clinical Cosmetic and Investigational Dermatology” In this review, the authors summarized non-pharmacological therapies that may promote hair growth and regeneration as alternatives to traditional drug treatments and hair transplantation, both of which have notable limitations.
30 citations
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April 2007 in “Dermatologic Clinics” This review discusses the mechanisms by which isotretinoin and hormonal therapy treat acne through their effects on sebaceous glands, reporting no new clinical results.
January 2013 in “Anti-infection Pharmacy” This review discusses the pharmacological and dermatological uses of Ligustri Lucidi Fructus and its components, such as anti-inflammation, anti-allergy, anti-dermatotumor effects, and hair growth promotion, but reports no new clinical results.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, Clitoria ternatea (Sangu Poo) was noted for its potential roles in health and skincare, with lab tests showing antioxidant, antimicrobial, liver-protective, and cancer-related activities; however, human trial evidence is lacking, impacting consistent quality and progress.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reviews the traditional and emerging medicinal uses of Clitoria ternatea Linn., highlighting its extensive chemical composition and potential health benefits, but notes the lack of human trial evidence and the need for better testing methods to ensure consistent quality and efficacy.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study highlights Clitoria ternatea's potential in modern health and skincare, noting its antioxidant, antimicrobial, and anti-inflammatory properties observed in lab tests and exploring its uses in beauty products, yet emphasizes the need for human trials to confirm benefits and ensure quality.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, Clitoria ternatea Linn., a plant from the pea family, is noted for potential health benefits, including antioxidant, antimicrobial, and anti-inflammatory effects, though human trial evidence is lacking and research on consistent quality is needed for practical applications.
16 citations
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April 2025 in “Foods” This study highlights the diverse applications of *Perilla frutescens* in traditional medicine, cuisine, and industrial settings, noting its significant antioxidant and antimicrobial properties in experimental models, as well as research efforts to enhance its bioactive content and ensure safety and standardization.
January 2026 in “International Journal of Molecular Sciences” This review highlights brimonidine’s potential as a dermatological agent, noting its ability to improve rosacea-related facial redness and its effectiveness in various other skin conditions due to its vasoconstrictive and anti-inflammatory actions, with minimal systemic absorption and a favorable safety profile for long-term use.
125 citations
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May 2019 in “Phytomedicine” This review discusses the historical development, mechanisms of action, and potential new clinical applications of the drug cepharanthine, highlighting its multi-faceted pharmacological properties; it reports no new clinical results.
2 citations
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June 2025 in “Molecules” This review highlights that extracts from *Hamamelis virginiana* (witch hazel) exhibit antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties in various studies, showing promise for future therapeutic use in dermatology and cosmetology, particularly for skin treatments.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that rice water, containing essential minerals and vitamins, shows promise in cosmetic and dermatological applications by acting as an anti-aging agent, hair growth promoter, and natural antidandruff treatment due to its antioxidant and antifungal properties.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that rice water, rich in minerals, vitamins, and amino acids, shows potential in cosmetics and dermatology for its hydration, anti-aging, and antioxidant properties and effectiveness against dandruff, while also promoting hair growth and scalp health with natural cleansing abilities.
25 citations
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February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, topical application of the SCD1 inhibitor XEN103 significantly reduced sebaceous gland size and number in mouse skin, suggesting potential local therapeutic effects for acne treatment without systemic side effects.
June 2010 in “Melanoma research” This study found that LDE225, a novel Smo antagonist, shows potential as a topical treatment for basal cell carcinoma due to its high affinity binding and effective inhibition of tumor growth in preclinical models.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the diverse pharmacological properties and applications of guava leaves, attributing their effectiveness to a rich phytochemical composition and modern extraction techniques, suggesting their potential as natural therapeutic agents across pharmaceutical, nutraceutical, and cosmeceutical fields.
130 citations
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August 2015 in “Experimental Dermatology” This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review explores the significant potential of guava leaves as a source of natural therapeutic agents, noting their rich phytochemical content and diverse pharmacological properties, such as antioxidant and anti-inflammatory effects, which may support their application in pharmaceutical, nutraceutical, and cosmeceutical industries.
4 citations
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January 1998 in “Heterocycles” Researchers made two new compounds that could be used for medicine.
October 2024 in “University of Thi-Qar Journal of Medicine” This study found that PRP therapy, topical treatments, and pharmacological interventions were effective in reducing hair loss among adults in Sulaimani Province.
2 citations
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November 2025 in “International Journal of Molecular Sciences” This review reports that chitosan, a versatile polysaccharide, shows potential for various therapeutic applications due to its chemical modifications, notably in treating non-communicable diseases and wound healing, though further clinical study is needed to confirm these benefits.
January 2023 in “IntechOpen eBooks” This chapter reviews various synthetic methods for creating pharmacologically active diazines, particularly focusing on pyrimidines, and discusses their potential in clinical applications. It also examines novel synthetic strategies that improve the drug-like qualities and safety profiles of these compounds.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the dual nature of Abrus precatorius as both a traditional medicine and a toxin, emphasizing its rich phytochemical profile and potential therapeutic applications, while noting the need for rigorous quality control and clinical trials to ensure safety and efficacy.
This scoping review identifies various pharmacological agents and five key mechanistic strategies being studied in vivo to mitigate multi-organ toxicity caused by cytarabine, with apraglutide and N-acetylcysteine highlighted as promising candidates for clinical application.
5 citations
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December 2022 in “Toxins” This review discusses the structural properties, pharmacological effects, and clinical applications of neurotoxins on synapses, reporting no new experimental results.
3 citations
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June 2023 in “Molecules/Molecules online/Molecules annual” The researchers reviewed cepharanthine, a long-used bisbenzylisoquinoline alkaloid, for its antiviral properties, including significant inhibition of SARS-CoV-2. They discussed cepharanthine's other pharmacological actions, highlighted plasma membrane fluidity as a key antiviral mechanism, and examined its safety, bioavailability, and potential for new clinical applications.