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STK11 gene polymorphism does not predict metformin response in PCOS.

The study suggests that analyzing DNA can help treat hair loss, but more research is needed.

More precise, personalized therapies are needed for autoimmune diseases.

Taking 1 mg of finasteride daily can increase hair count and improve hair appearance, but it may have side effects on sexual function and a potential risk of prostate cancer. It may not be effective for postmenopausal women unless taken in higher doses.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.

The most effective treatments for hair loss are minoxidil, finasteride, PRP, and hair transplants, with steroids and immunosuppressants for autoimmune types.

2011 dermatology discussions highlighted stem cell hair treatments, new lichen planopilaris therapies, skin side effects from cancer drugs, emerging allergens, and the link between food allergies and skin issues.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Case-only trees and random forests improve predictions of treatment effects in clinical trials.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.

Suppressing certain hormones might help prevent prostate cancer.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Juniperus plants contain compounds with potential for developing various medical treatments.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Alopecia areata has a complex genetic basis that was not fully understood as of 2001.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.