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This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.

Progesterone reduces anxiety without needing progesterone receptors.

This study found that GhPLDα1 in upland cotton may be involved in fiber development, correlating with increased hydrogen peroxide and cellulose biosynthesis during secondary cell wall thickening.

This study reports that the transgenic expression of Dsg1 in mice rescued the severe B6-Dsg3−/− phenotype and created a syngeneic mouse model of pemphigus vulgaris, which may aid in understanding autoimmunity mechanisms.

This study found that total glucosides of paeony (TGP) reduced hair loss and inflammation in alopecia areata mice by inhibiting cellular pyroptosis.

This review discusses the role of PPAR-γ in the pathogenesis of primary cicatricial alopecia, including its involvement in lichen planopilaris and treatment trials using PPAR-agonists, and reports no new clinical results.

This study suggests that the Grasp protein may play a role in regulating skin homeostasis following UVB exposure by influencing p53-mediated apoptotic responses in mice.

This study found that 15-dPGJ2 promotes apoptosis in human follicular keratinocytes, suggesting its potential role in developing hair loss prevention treatments through DP2 antagonism.

Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.

This study found that mice lacking sPLA2-IIE had distinct skin abnormalities, particularly affecting hair follicles, highlighting the differing roles of sPLA2 isoforms in mouse skin.

This study found that loss of the Ptch2 receptor in mice leads to increased incisor growth and enhanced mesenchymal stem cell differentiation, highlighting Ptch2's role in organ regenerative potential.

In this study, Panax ginseng extract and its ginsenosides were found to stimulate the proliferation of hair-related cells and promote the transition from the telogen to the anagen phase, enhancing hair-shaft growth by suppressing BMP4 expression in human dermal papilla cells.

In this study, the expression of Gnαs was significantly higher in black mice compared to white mice, suggesting its potential involvement in coat color formation in mice.

This study found that BRG1 is crucial for keratinocyte migration during skin wound healing, as its suppression impairs wound closure by inhibiting migration without affecting cell proliferation or apoptosis.

In this study, a transgenic mouse model suggested that suppressing the expression of the HGPS mutation may reverse disease symptoms, including skin abnormalities, supporting the potential for treatment development.

This study found that ultra-high molecular weight poly-γ-glutamic acid promoted hair growth in telogenic C57BL/6 mice by inhibiting 5-alpha reductase activity and inducing the anagen phase.

This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.

PH-762 shows promise in treating skin cancer by effectively targeting and silencing PD-1 in tumors with minimal side effects.

This study found that ginsenoside Rg3 significantly inhibited melanogenesis in human melanocytes and B16F10 cells by activating the ERK pathway, suggesting potential as a skin-whitening agent.

This study suggests that PDGFA and BMP2 play a role in the hair follicle cycle in cashmere goats, with PDGFA particularly involved in activating the growth phase.

This study found that inhibiting the gp130 Y814 signaling module promotes tissue regeneration and may prevent pathological outcomes after injury in animal models.

This study suggests that phloroglucinol may enhance anagen signaling and reduce oxidative stress-induced damage in human dermal papilla cells, offering a potential therapy for hair loss.

This study found that sebaceous glands can regenerate after PPARg deletion in adult skin, relying on the hair cycle and FGFR signaling.

This study suggests that AKR1C3 expression may influence PGD2-related pathways in skin squamous cell carcinoma and potentially be involved in androgenetic alopecia, although further investigation is needed to clarify its role.

This study found that a phosphorus starvation-insensitive mutant of Arabidopsis thaliana shows altered root growth and auxin responses under low phosphate conditions compared to wild-type plants, suggesting a role for LPR1 in regulating these traits.

In this study, the authors used AI-driven methods to identify and prioritize promising therapeutic targets that may address both aging and Glioblastoma Multiforme, proposing CNGA3, GLUD1, and SIRT1 as novel candidates.

This study found cell-specific variations in POMC mRNA and peptide expression in murine skin, suggesting that PC1 and PC2 convertases contribute to differential POMC processing.

This article reviews the potential of using PBM in 3D tissue engineering to improve cell viability under stress conditions but reports no new experimental findings.

This study found that serum PGRN levels and HOMA-IR were significantly higher in male AGA patients compared to controls, suggesting a link to insulin resistance and metabolic syndrome.