Transgenic Rescue of Desmoglein 3 Null Mice with Desmoglein 1 to Develop a Syngeneic Mouse Model for Pemphigus Vulgaris

April 2011 in “ Journal of Dermatological Science ”

Tsuyoshi Hata, Koji Nishifuji, Kouji Shimoda, Takashi Sasaki, Taketo Yamada, Takeji Nishikawa, Shigeo Koyasu, Masayuki Amagai

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Research cited in this study

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research Differential Structural Properties and Expression Patterns Suggest Functional Significance for Multiple Mouse Desmoglein 1 Isoforms

29 citations , October 2004 in “Differentiation”

Multiple mouse desmoglein 1 isoforms have distinct roles in skin and hair development.

Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation

research Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation

108 citations , July 2002 in “Molecular and cellular biology”

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

research Expression of Desmoglein 1 Compensates for Genetic Loss of Desmoglein 3 in Keratinocyte Adhesion

72 citations , July 2002 in “Journal of Investigative Dermatology”

Desmoglein 1 can partly make up for the loss of Desmoglein 3 in hair adhesion but not in mucous membranes.