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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Skin problems are very common in people with end-stage kidney disease.

No cure for female pattern hair loss, but various effective treatments exist.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

Goat reproductive activity and coat growth are affected by light and temperature, with temperature altering prolactin levels and hair growth, but not melatonin or estrus onset.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.