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This review reports that the treatment of androgenetic alopecia is shifting from single therapies to personalized, multimodal approaches incorporating both traditional and emerging pharmacologics, regenerative strategies, nutraceuticals, cosmeceuticals, and device-based interventions, with combination regimens showing improved outcomes.

This issue contains notes by Dr. Bradley Wolf and mentions comments by Dr. Jerry Cooley, but it presents no new research findings.

This study explored the in vitro skin penetration of two compounds from Tectona grandis leaf extract used for standardization and found that compound 1 penetrates more efficiently than compound 2, especially with a propylene glycol enhancer.

In this multicenter observational study, researchers found that using micrografts with human follicle mesenchymal stem cells increased hair density significantly in both male and female patients with mild to moderate androgenic alopecia after 12 months, suggesting a viable alternative for hair regrowth.

This paper reviews the development of transdermal drug delivery systems for skin diseases, from first to fourth generation, and highlights ongoing challenges and the importance of clinical trials, but provides no new clinical results.

This review highlights that gut dysbiosis and bacterial extracellular vesicles are key factors in PCOS pathophysiology, and suggests AI-driven analysis of these profiles could enhance diagnostic accuracy and treatment personalization, though ethical concerns like data privacy and bias must be considered.

This review discusses various skin reactions after SARS-CoV-2 infection and COVID-19 vaccination, noting a higher incidence with mRNA vaccines than adenovirus vector vaccines, and reports no new clinical results.

This review highlights that post-oncologic skin suffers from several impairments following cancer treatments, and dermocosmetic strategies, particularly those involving nanocarriers, can enhance the efficacy and stability of antioxidants, thereby aiding skin regeneration and improving quality of life.

This review highlights the limitations of existing hair loss treatments like minoxidil and finasteride and suggests that future therapies may benefit from focusing on antibody and cell-based treatments, which offer targeted and potentially transformative options for managing hair loss disorders.

This source reports that for treating keloids and hypertrophic scars, combination pharmacotherapy targeting multiple sites is generally more effective than using a single drug, though outcomes of individual therapies vary and the development of satisfying treatments is ongoing.

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.

This review highlights the diverse roles of melanocytes in pigmentation, immunity, and hearing among other functions, their involvement in disorders, and their emerging potential in regenerative medicine, including applications in disease modeling and therapy development using advanced technologies.

This study found that applying 0.005% latanoprost topically to eyelashes significantly increased their length and darkened their color in healthy volunteers over three months, without causing any side effects or changes in intraocular pressure compared to a placebo.

This study found that macrophage extracellular vesicles enriched with Wnt proteins significantly promoted hair follicle growth in mice and increased hair shaft size in human hair follicles, suggesting potential clinical use for treating hair loss.

This review discusses the potential of secretome derived from stem cells for treating alopecia areata and reports no new clinical results; the authors suggest the need for further human trials.

This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.

This narrative review highlights the potential of exosomes in regenerative and aesthetic dermatology, particularly in India, but emphasizes that their clinical use is still investigational due to limited and diverse study data, insufficient long-term safety information, and regulatory challenges.

This review discusses the similarities between COVID-19 and acute radiation syndrome, highlighting their shared inflammatory responses and suggesting that insights from radiation biology could inform COVID-19 research and treatment approaches; it reports no new clinical results.

This review discusses current and emerging therapies for androgenetic alopecia, emphasizing regenerative treatments and nanotechnology advancements, but it reports no new clinical results.

This review discusses recent advances in the therapeutic potential of exosomes for wound healing, highlighting their benefits and challenges but reports no new clinical results.

This review highlights the promise of non-viral gene delivery systems, particularly genosomes, over traditional viral vectors due to enhanced safety and efficiency in therapeutic nucleic acid delivery for genetic diseases like cystic fibrosis and malignancies.

This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.

This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.

This study suggests that dermal stem/progenitor cells can be enriched by intracellular granularity and display high proliferation and differentiation potential in vitro, distinguishing them from other fibroblasts and progenitors.

This article reports a case of macular amyloidosis associated with myelofibrosis with myeloid metaplasia, a combination not previously documented.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.

This study found that applying topical thymidine dinucleotide (pTT) to newborn mice before UV exposure delayed and reduced melanoma development compared to untreated controls.

This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.

This study found that PEGylated LUT-Aspasomes significantly improved neuroprotective effects in stressed rats, enhancing spatial memory, reducing depressive-like behavior, and preserving hippocampal architecture better than free luteolin. Additionally, it increased brain delivery and stability, suggesting potential for treating stress-related neurobehavioral disorders.