11 citations
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January 2008 in “International journal of environment and health” This review discusses the environmental contamination and health risks of Platinum Group Elements, highlighting their potential bioaccumulation and associated health issues, especially in vulnerable populations like children, and reports no new experimental findings.
July 2020 in “Vestnik urologii” This review examines the contentious issue of post-finasteride syndrome linked to 5-alpha reductase inhibitors and reports mixed findings on its sexual, physical, and psychological effects; the authors call for more rigorous studies.
1 citations
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July 2018 in “Current Sexual Health Reports” This review discusses the occurrence of persistent sexual, physical, neurological, and psychiatric side effects known as post-finasteride syndrome after 5x-reductase inhibitor treatment, and emphasizes the importance of evaluating these risks for patients with benign prostatic hyperplasia or androgenic alopecia.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This policy brief found that post-drug syndromes are under-recognized in current pharmacovigilance systems, leading to inadequate risk assessments and prolonged patient harm from persistent drug-induced conditions.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper proposes that gut dysbiosis plays a crucial role in Post-Finasteride Syndrome by possibly contributing to both androgenic and non-androgenic symptoms, and may explain fluctuating symptom cycles better than static genetic explanations.
October 2024 in “Journal of the Endocrine Society” This case study describes a 45-year-old man who developed post-finasteride syndrome with various symptoms after stopping Finasteride, highlighting the condition's rarity and poorly understood pathophysiology.
30 citations
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January 2020 in “Fertility and Sterility” This review discusses the evidence for post-finasteride syndrome as a condition potentially induced by finasteride and dutasteride, associating them with sexual dysfunction, depression, anxiety, and suicidal ideation in a subset of men, and reports no new clinical results.
8 citations
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July 2018 in “Current Sexual Health Reports” This review discusses post-finasteride syndrome, emphasizing its serious psychological and cognitive symptoms and the need for more research and awareness in the medical community, but provides no new clinical findings.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This policy brief highlights that post-drug syndromes remain under-recognized in pharmacovigilance, leading to inadequate risk assessments and patient care. It identifies systemic failures in current frameworks and recommends actions to improve long-term drug safety monitoring and education, affecting public health outcomes significantly.
July 2018 in “European Medical Journal” This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.
49 citations
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January 2003 in “Clinical and Experimental Dermatology” This report from the UK reviews the literature on post-menopausal frontal fibrosing alopecia and highlights its under-recognition and distinctive characteristics compared to lichen planopilaris, but does not provide new results.
11 citations
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January 2018 in “International Journal of Trichology” This commentary reviews the post-Finasteride syndrome and argues that while the condition's validity is debated, comprehensive guidelines are needed to address related risks and treatment options; it reports no new clinical results.
October 2012 in “Sax's Dangerous Properties of Industrial Materials”
14 citations
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January 2019 in “Skin appendage disorders” This paper discusses the first reported case of post-finasteride syndrome in a long-term dermatotrichology setting, occurring in a 25-year-old male after dutasteride treatment, and highlights possible links to mental health disorders.
23 citations
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October 2008 in “Journal of medicinal chemistry” This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.
8 citations
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May 2016 in “Indian Journal of Pharmacology” This case report describes an atypical postfinasteride syndrome in a patient treated with both dutasteride and finasteride for androgenic alopecia, highlighting its multisystem involvement and irreversible nature.
This study examined data from the FDA Adverse Event Reporting System and found that finasteride use is linked with both known and previously unlisted adverse events, such as erectile dysfunction and post-5α reductase inhibitor syndrome, with variations observed by age and sex.
April 2016 in “The Journal of Sexual Medicine” PFS affects some women, steroids easily bought online, hypogonadism info unreliable, low testosterone linked to CVD.
39 citations
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May 2006 in “Molecular Plant-Microbe Interactions” This study suggests that fusaric acid at nontoxic concentrations may activate signal transduction in plants which could aid in the plant-defense responses against Fusarium spp.
January 2022 in “Archivos españoles de urología” This review examines global literature on post-finasteride syndrome, finding few studies link finasteride to rare sexual and systemic adverse effects; it is the first such review conducted in Spain.
This study found that women with polycystic ovary syndrome had significantly higher levels of the protein fetuin-A compared to healthy controls.
May 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This article evaluates clinical and scientific literature on post-finasteride syndrome, concluding that finasteride and dutasteride may cause persistent sexual, neurological, and physical adverse side effects in a subset of men.
July 2022 in “Research Square (Research Square)” This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.
2 citations
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July 2021 in “The Journal of Sexual Medicine” This study found significant differences in gene expression, particularly in androgen receptor activity, between men with post-finasteride syndrome and healthy controls, suggesting a potential biological basis for the syndrome.
In this study, researchers found that female rats exhibited more pronounced panic-related escape behavior during hypoxia, particularly in the diestrus phase, and that low-dose fluoxetine reduced this behavior, suggesting its potential for managing panic disorder symptoms related to hormonal cycles in women.
7 citations
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December 2023 in “International Journal of Molecular Sciences” This study demonstrated that Forsythiaside A protected against oxidative stress in both cell models and a mouse model of liver damage, suggesting its potential as a liver-protective agent.
November 2016 in “Hair transplant forum international” This article summarizes Dr. Alan Jacobs's presentation at the 2016 ISHRS World Congress but reports no new research findings.
20 citations
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November 2019 in “International Journal of Environmental Research and Public Health” This study found that high exposure to air pollutants like SO2, NO, NO2, NOx, and PM2.5 was linked to a significantly increased risk of developing PCOS in women.
This study developed a new analytical method to identify a wide range of endocrine disrupting compounds in full-term amniotic fluid, revealing diverse substances with potential endocrine activity.
January 2020 in “Archives of urology” This review discusses concerns about persistent side effects of finasteride, such as sexual dysfunction and suicidal ideation, urging the medical community to recognize and address these issues.