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A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

The document concludes that better research methods are needed in men's sexual health to provide stronger evidence and improve patient care.

The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.

Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

Flutamide-induced hypospadias in rats slows down early wound healing.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

A 25-year-old Malay fireman had skin bumps on his neck that were removed successfully after other treatments failed.

Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.