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This study found that PDCD4 protein expression is reduced in various skin cancers compared to normal skin, suggesting its potential role in preventing or treating certain skin cancers.

This study found that a simple two-step method for preparing platelet-rich plasma produced satisfactory quality at a lower cost compared to many commercial systems, enabling smaller medical institutions to utilize PRP therapy.

In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.

The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.

This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.

This study found that hyperpigmentation following contact immunotherapy for severe alopecia areata may indicate poor treatment responsiveness and aligns with characteristics of pigmented contact dermatitis.

The researchers reported that their novel formulation of pterostilbene-loaded ethoniosomes with folic acid coating effectively targeted lung cancer cells in vitro and demonstrated promising results in animal models, indicating potential for future targeted chemotherapy applications.

In this study, male participants with early androgenetic alopecia experienced a significant increase in hair growth rate after applying topical lipoid cepharanthine lotion for six months.

This study found that topical BPM31543 was safe, tolerable, and showed potential to reduce chemotherapy-induced alopecia at higher dosing levels among adult women with cancer receiving taxane-based chemotherapy.

This study found that local PGE2 injection may prevent radiotherapy-induced hair loss by protecting hair follicle cells and promoting hair follicle self-repair.

In this study, researchers identified CENPV as a new CYLD interacting partner that localizes to primary cilia and regulates acetylated tubulin levels, offering insights into the pathogenesis of skin appendage tumors.

A new test helps find drugs to treat head and neck cancer by targeting c-Rel.

This study found that POD-loaded solid lipid nanoparticles using 0.5% poloxamer 188 and 1.5% soybean lecithin (P-SLN) improved epidermal targeting and POD accumulation in porcine skin compared to traditional tincture.

This study developed a legally valid, evidence-based informed consent document specifically for platelet-rich plasma injections, intended to enhance patient rights and communication, and support legal defense in malpractice cases.

This study found that PC 3DP models are reliable preclinical tools that could potentially customize treatment strategies and predict patient prognoses by correlating drug sensitivity profiles with clinical outcomes, though larger patient cohort validation is needed to confirm clinical utility.

This review discusses the progress and challenges of targeted protein degradation therapies, highlighting the increasing number of degraders in cancer clinical trials and the limited diversity in targeted proteins, primarily focusing on those employing CRL4^CRBN as the E3 ligase.

In this study, researchers compared three treatments for stable vitiligo and found that a combination of follicular cell suspension and mini punch grafting resulted in significantly better re-pigmentation after six months compared to using either method alone.

This study found that a chemotherapy regimen combining CMFVP and ACP treatments for unresectable metastatic breast cancer yielded a 66.7% overall response rate, with premenopausal women responding more favorably than postmenopausal women.

In this observational study, patients with androgenic alopecia or hair loss related to COVID-19 showed more significant hair regrowth when treated with combined pulsed electromagnetic field therapy and photobiostimulation therapy compared to photobiostimulation therapy alone, with a statistically significant increase in hair count.

In this study, ginsenoside 20(S)-protopanaxadiol-aglycone (PPD) was shown to downregulate androgen receptor expression and inhibit tumor growth in prostate cancer cells.

This study concluded that in female pattern hair loss patients, CGF and i-PRF treatments were more effective than PRP in increasing target area hair count, with i-PRF having the lowest adverse event rate.

In this study, clinically used preoperative skin preparations with povidone iodine and chlorhexidine gluconate did not meet FDA log-reduction standards for bacterial bioburden in a porcine model, suggesting persistent infection risks.

This study found that platelet-rich plasma may be more effective and satisfactory than topical clobetasol for treating lichen planopilaris over six months.

In this study, PKC ε transgenic mice exposed to ultraviolet radiation showed increased hair follicle stem cell frequency and altered gene expression compared to wild-type mice, suggesting a potential role in skin cancer susceptibility.

This article discusses the potential of finasteride as a chemopreventive agent for prostate cancer and highlights unresolved issues, but it reports no new research findings.

In this study, injecting dermal sheath cup cells into affected areas of pattern hair loss improved hair thickness and patient-reported hair appearance in 62.9% of the participants, with better results in women, without serious side effects.

CGF-PF may improve hair loss treatment by targeting hair follicle stem cells more effectively.

This pilot study suggests that platelet-rich plasma may be a promising treatment for chronic telogen effluvium with good safety, and cost-effective preparation methods may be reliable alternatives to more expensive ones.

This case series highlights the real-world challenges and experiences of US healthcare providers using pegvaliase for phenylketonuria treatment, emphasizing patient education on adverse events and dietary changes, and tailored titration schedules, while reporting that most patients achieved treatment efficacy despite initial adverse events.

This article describes the PHAT technique for lip and facial rejuvenation but reports no new clinical findings; the technique aims to improve skin quality and enhance surgical outcomes.