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Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Women with PCOS often experience anxiety, depression, and a lower quality of life.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Both mouse and rat models are effective for testing alopecia areata treatments.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

Melatonin may reduce skin damage caused by X-rays in rats.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.

Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.

Niosomes improve minoxidil skin penetration for hair loss treatment.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.