54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
54 citations,
June 2020 in “Pharmaceutics” New nanocarriers improve drug delivery for disease treatment.
54 citations,
September 2002 in “Annals of Pharmacotherapy” Herbal treatments can help with early-stage BPH symptoms, but more research is needed.
49 citations,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
49 citations,
March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
48 citations,
August 2010 in “PubMed” Chemotherapy often causes hair loss, which is distressing for many, but usually reversible.
48 citations,
March 2005 in “PubMed” Some plant-based compounds might help control the growth of new blood vessels if further research confirms their effectiveness.
48 citations,
February 1999 in “PubMed” Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.
48 citations,
April 1995 in “PubMed” Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.
46 citations,
October 2018 in “JCI insight” CD8+ T cells are involved in alopecia areata and may cause disease relapse.
45 citations,
November 2021 in “Fertility and Sterility” The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.
42 citations,
April 2021 in “JCI insight” Blocking JAK3 signaling can reverse hair loss from alopecia areata.
41 citations,
August 2015 in “The FASEB Journal” Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
39 citations,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
39 citations,
June 2019 in “Nanomaterials” Nanotube-based hair treatments could improve hair health and growth, and offer long-lasting effects.
39 citations,
September 2018 in “American Journal of Medical Genetics Part A” A new genetic mutation in the ODC1 gene causes developmental delay and other symptoms in a young girl.
38 citations,
May 2000 in “Livestock production science” Giving high-quality protein or methionine supplements helps improve hair growth in Angora goats and, to a lesser extent, in Cashmere goats.
37 citations,
October 2021 in “Nutrients” Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.
37 citations,
September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
37 citations,
July 1980 in “PubMed” Hair lotions with 17 alpha-estradiol can reduce hair loss but won't regrow new hair.
36 citations,
June 2012 in “PubMed” There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.
36 citations,
August 2009 in “PubMed” The review suggests seeing a dermatologist for scarring hair loss and using treatments like minoxidil or finasteride for common male and female pattern hair loss.
35 citations,
September 2017 in “PubMed” The document concludes that hair loss has many causes and treatments vary, including medication for pattern baldness and addressing underlying issues for other types.
34 citations,
July 1993 in “PubMed” 33 citations,
September 2005 in “PubMed” Dutasteride successfully treated a woman's hair loss when other treatments failed.
32 citations,
July 2016 in “PubMed” 5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.
32 citations,
January 2006 in “Liver transplantation” Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
31 citations,
June 2001 in “PubMed” TrichoScan accurately measures hair growth and showed improved hair counts and thickness after finasteride treatment.
31 citations,
January 2001 in “PubMed” 30 citations,
August 2021 in “Journal of Ethnopharmacology” Akebia quinata and Akebia trifoliata have many health benefits and potential medical uses.