May 2024 in “Open Repository of the University of Porto (University of Porto)” This report details the experiences gained during a pharmacy internship in both hospital and community settings, highlighting the preparation of sildenafil suspensions for hospital use, patient consultations on autoimmune conditions, and educational material creation in community pharmacy, alongside insights into diabetes and ADHD treatments.
October 2023 in “Open Repository of the University of Porto (University of Porto)” In this study, a pharmacy internship report describes a six-month community pharmacy internship, detailing activities to promote sleep quality, sun protection, hypertension screening, and detecting medication errors, as well as in-depth discussions on smoking cessation and alopecia treatments.
January 2016 in “Springer eBooks” This review discusses medications used in dermatology, detailing their side effects and interactions, and reports no new clinical results.
6 citations
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July 2025 in “Cancer Medicine” This study reported that ZSYY001, a nanoparticle formulation of polymeric micellar paclitaxel, showed promising antitumor activity and was safe and well-tolerated in preclinical models and a phase I trial, without acute hypersensitivity reactions at doses up to 390 mg/m².
134 citations
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July 2020 in “Experimental dermatology” This review discusses immune privilege in anagen hair follicles and its collapse in alopecia areata, emphasizing the importance of restoring this function for effective management and disease relapse prevention.
84 citations
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June 2024 in “BMC Public Health” This study observed that while TikTok offers the best flow for videos on laryngeal cancer, YouTube provides higher quality, but video quality overall needs professional enhancement and platform algorithm improvements.
74 citations
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August 2023 in “Frontiers in Immunology” In this review, the authors explored the diverse roles of fibroblasts in wound healing, suggesting that understanding their complexity could lead to better insights into wound pathologies and the development of new treatments.
29 citations
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November 2015 in “Acta Biomaterialia” This study found that water-filtered infrared A radiation can induce the release of a model drug from gold nanoparticle-doped particles in hair follicles in an ex vivo porcine skin model, suggesting feasibility for follicular drug delivery systems.
15 citations
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June 2025 in “Journal of Extracellular Vesicles” This review examines various methods for purifying extracellular vesicles loaded with drugs, highlighting their principles, benefits, and drawbacks, and stresses the importance of standardized guidelines to enhance the reproducibility of EV-based drug delivery research.
October 2023 in “Biomaterials” This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.
96 citations
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September 2021 in “International Journal of Molecular Sciences” This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.
11 citations
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June 2025 in “Polymers” This review reports on recent surfactant-based niosome formulations, including those with polysaccharides, for versatile drug delivery applications such as ocular, oral, and transdermal settings, while discussing their limitations and potential prospects.
25 citations
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April 2021 in “The EMBO Journal” This review discusses the role of hair follicle stem cells as active signaling centers in skin homeostasis, highlighting recent advancements and reporting no new clinical results.
1 citations
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February 2024 in “Pharmaceutics” This review highlights recent developments in nanovesicular carriers for enhancing molecule delivery into and across the skin, focusing on the design and evolution of phospholipid and non-phospholipid systems used in cosmetics and treating various skin conditions.
1 citations
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September 2023 in “International Journal of Dermatology” In this study conducted at a tertiary dermatological clinic, researchers identified and described the clinical, dermoscopic, and histopathological features of preclinical folliculitis keloidalis, including novel dermoscopic findings such as perifollicular scale, which was associated with fibrosis.
In this study, the researchers developed a biomimetic multilayer composite scaffold combining a decellularized amniotic membrane, fibroblast-laden collagen gel, and epidermal stem cells, which healed full-thickness skin wounds more quickly and effectively by regenerating hair follicles without scarring compared to Moropicin ointment.
This literature review on neurocosmetics found that both nature-derived peptides and synthetic molecules can improve skin concerns like aging and pigmentation, while also promoting emotional well-being; however, gaps in long-term efficacy and personalized approaches remain.
37 citations
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December 2022 in “Acta Pharmaceutica Sinica B” This review discusses the strategies and potential of CRISPR delivery for gene therapy, highlighting the challenges and innovative use of stimuli-responsive nanocarriers, but reports no new experimental results.
25 citations
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June 2024 in “Pharmaceutics” This review highlights the potential of scaffold-based drug delivery systems to revolutionize oral cancer treatment by enhancing targeted and localized drug administration, reducing systemic side effects, and providing environments conducive to non-cancerous cell growth, though challenges like scalability and biocompatibility remain.
9 citations
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January 2021 in “BioMed research international” This study describes a method to extract and characterize keratin particles from human hair, finding they can encapsulate the anticancer drug Paclitaxel with significant efficiency, releasing it in a pH-dependent manner potentially beneficial for targeted cancer treatment.
2 citations
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September 2025 in “Antioxidants” This review highlights that nano-antioxidants show promise as a treatment strategy for immune-mediated inflammatory diseases, like autoimmune and chronic inflammatory conditions, due to their improved stability and targeted delivery, but notes that further research is necessary to optimize their use and assess long-term safety.
148 citations
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September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.
98 citations
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November 1999 in “Dermatology Online Journal” This review discusses the effects of IGF-1 on hair follicle cell proliferation and differentiation, highlighting its roles in paracrine signaling, apoptosis prevention, and hair growth, but reports no new clinical results.
96 citations
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April 2017 in “Oncotarget” This study found that nanoemulsions of different sizes vary in their ability to penetrate skin layers, with smaller sizes aiding transdermal delivery and potential applications in transcutaneous immunization.
92 citations
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February 2023 in “Antibiotics” This review discusses advances in nanomaterial-based wound dressings for infection control, highlighting their ability to detect and treat bacterial infections effectively, but reports no new clinical results.
81 citations
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October 2023 in “Bioactive Materials” This review highlights the promising potential of 3D printing for creating microneedles with precise customization and improved performance compared to traditional micromolding, emphasizing applications in personalized medical devices and advancements in biomedical fields.
76 citations
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January 2022 in “Journal of Tissue Engineering” This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.
54 citations
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June 2020 in “Pharmaceutics” This review discusses the advancements in using "soft" colloidal nanocarriers for delivering photosensitive agents and highlights their potential applications in treating diseases like cancer, but it reports no new clinical results.
46 citations
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August 2022 in “Animals” This study identified key genes and miRNAs involved in feather morphogenesis in Zhedong White geese, highlighting a negative correlation between FOXO3 and miR-144-y.
46 citations
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January 2020 in “Research” This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.