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Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

Hirsutism, excessive hair growth in women, is often caused by PCOS and can be managed with medication and personalized treatment plans.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

PSA might help diagnose PCOS and related skin issues, but more research is needed.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.