13 citations,
March 2014 in “Cutaneous and Ocular Toxicology” Oral isotretinoin for severe acne can change hormone levels but does not significantly affect ovarian function.
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4 citations,
January 2014 in “Indian Journal of Endocrinology and Metabolism” Indian women with PCOS may need different ultrasound criteria for diagnosis than current standards.
36 citations,
May 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.
4809 citations,
January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
40 citations,
January 2010 in “Annales D Endocrinologie” The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.
8 citations,
April 2019 in “Journal of the Endocrine Society” Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.
35 citations,
March 2012 in “Experimental and Clinical Endocrinology & Diabetes” The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.
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11 citations,
November 2006 in “Journal of Veterinary Diagnostic Investigation” An alpaca acted like a male and couldn't have babies because of a benign tumor in its ovary that caused high testosterone levels.
212 citations,
May 2010 in “American Journal of Obstetrics and Gynecology” Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.
2 citations,
November 2017 in “Gynecological Endocrinology” The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.
August 2023 in “Malaysian Journal of Medicine and Health Sciences/Malaysian journal of medicine and health sciences” Pueraria mirifica extract may help treat benign prostatic hyperplasia.
October 2023 in “International Journal For Multidisciplinary Research” Women with PCOS face many health risks, but exercise, a healthy diet, and weight management can help.
1 citations,
April 2022 in “International journal of Ayurveda and pharma research” Ayurvedic treatment helped improve PCOD symptoms and ultrasound results.
124 citations,
July 1997 in “Journal of Biological Chemistry” Overexpressing a specific enzyme in mice causes hair loss and female infertility.
December 2018 in “Actas urológicas españolas” 5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.
28 citations,
August 2014 in “Journal of Assisted Reproduction and Genetics” The VEGF +405G allele may increase the risk of PCOS in South Indian women.
58 citations,
January 2013 in “The Journal of Clinical Endocrinology and Metabolism” Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
14 citations,
January 2008 in “Gynecological Endocrinology” High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.
April 2024 in “Journal of cancer research and clinical oncology” Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
July 2023 in “International Journal of Endocrinology” Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.
6 citations,
January 2010 in “Neoplasma” Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.
20 citations,
March 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
66 citations,
January 2001 in “Vitamins and hormones” Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
105 citations,
April 2014 in “Trends in Pharmacological Sciences” Targeting the Smoothened receptor shows promise for treating certain cancers.
16 citations,
February 2018 in “European Journal of Endocrinology” Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
3 citations,
July 2022 in “Problemy èndokrinologii” Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.
36 citations,
November 2009 in “European Radiology” The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.
9 citations,
May 2008 in “Journal of Clinical Oncology” A woman's ovarian tumor causing high testosterone was successfully removed, and her symptoms improved.
1 citations,
July 2015 in “AACE clinical case reports” Removing both ovaries treated the woman's excess male hormone symptoms.
59 citations,
August 2007 in “Clinical Endocrinology” The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.