research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis
Mice without certain skin proteins had abnormal skin and hair development.
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research Large-Scale Cultivation of Transplantable Dermal Papilla Cellular Aggregates Using Microfabricated PDMS Arrays
Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
research 5α-Reductase Inhibitors: A New Hope in Dermatology?
Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
research The Arrector Pili Muscle: The Bridge Between the Follicular Stem Cell Niche and the Interfollicular Epidermis
The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.
research Inflammatory Perifollicular Fibrosis And Alopecia
Inflammation around hair follicles leads to hair loss, and treatments should focus on reducing this inflammation and other factors for effectiveness.
research Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review
Caffeine improves hair growth, thickness, and reduces shedding.
research Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intradermal Nevus
The conclusion is that Pigmented Epithelioid Melanocytoma can start from hair follicle stem cells or from a mole on the skin.
research Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response
Topical booster improves hair loss treatment effectiveness.
research Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evolutionary Development
Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.
research Catalytic-Dependent and -Independent Activities of Polycomb Repressive Complex 1 Differentially Regulate Skin Stem Cell Specification
PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
research Abstracts
Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.
research Alopecia Areata Update
Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
research Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study
The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.
research Permanent Chemotherapy-Induced Alopecia: Case Report and Review of the Literature
Some chemotherapy can cause permanent hair loss.
research Epidermal Stem Cells: Practical Perspectives and Potential Uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Traction Alopecia: The Root of the Problem
Tight hairstyles and chemical relaxers can cause hair loss known as traction alopecia.
research Regulation of Melanocyte Stem Cells in the Pigmentation of Skin and Its Appendages: Biological Patterning and Therapeutic Potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research Low-Dose Oral Minoxidil for Treating Alopecia: A 3-Year North American Retrospective Case Series
Low-dose oral minoxidil is an effective and well-tolerated treatment for hair growth in alopecia patients.
research Androgenetic Alopecia: Update on Etiology
AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
research Alpha Smooth Muscle Actin Role in Androgenetic Alopecia Pathogenesis
Reduced alpha smooth muscle actin may cause hair loss in androgenetic alopecia.
research Randomized Non-Inferiority Study of Oral Minoxidil (1.25 mg/day) vs. 5% Topical Minoxidil in Treating Female Pattern Hair Loss
Oral minoxidil is as effective and safe as topical minoxidil for treating female pattern hair loss.
research Use of Rice Water (Oryza Sativa) and Hibiscus (Hibiscus Rosa-Sinensis)
Rice water and hibiscus can help improve hair health and growth.
research Evaluation of the Relationship Between Androgenetic Alopecia and Blood Groups and Rhesus Factor
No link between hair loss and blood groups or Rhesus factor.
research Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research Effects of Nitric Oxide on Skin Burn Wound Healing
Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
research Androgens in Women: Role in Androgen-Mediated Cutaneous Disorders
Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
research Bi-Allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex
Mutations in the LSS gene cause a rare type of hereditary hair loss.
research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16
K16 can partially replace K14 but causes hair loss and skin issues.
research Alopecia in Patients Treated with Molecularly Targeted Anticancer Therapies
Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.